CurrentAnesthesia — ICU sedation, delirium & recovery

Environmental scan of Indigenous resources and culturally specific tools across intensive care units in Alberta, Canada

2026-10-28T10:36:56.498Z

Research article · Can J Anaesth, 2026.

Association of Days Alive and at Home at Day 90 After Intensive Care Unit Admission With Long-term Survival and Functional Status Among Mechanically Ventilated Patients

2026-10-28T04:44:26.953Z

Secondary analysis · JAMA Netw Open, 2023. Mortality at 1 year after ICU admission (survivors to day 90) — Tertile 1 vs Tertile 3: aHR for death 0.18 (95% CI 0.07-0.43); P < .001; lower DAAH90 associated with higher mortality

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial

2026-10-28T04:43:30.217Z

Secondary analysis · JAMA, 2023. Survival through day 180, 180 days — IL-6 receptor antagonists vs Control: adjusted HR for death (HR<1 = improved survival) 0.74 (95% CrI 0.61-0.90); >99.9% probability of improving 6-month survival

Health Expectations and Quality of Life After Acute Respiratory Failure: A Multicenter Prospective Cohort Study

2026-10-28T04:40:50.491Z

Cohort study · Chest, 2023. WHOQOL-BREF domain scores, 6 months after discharge — Met vs Unmet: estimated difference in scores (median) 19; P < .001; physical health; IQR 12-15

New and Persistent Sedative Prescriptions Among Older Adults Following a Critical Illness: A Population-Based Cohort Study

2026-10-28T04:40:50.491Z

Cohort study · Chest, 2023. New sedative prescription within ≤ 7 days of discharge: Filled a new sedative prescription 15,277 (6.1%)

Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: a randomised controlled trial

2026-10-28T04:39:17.656Z

Randomised controlled trial · Lancet Respir Med, 2023. Cognitive impairment (Montreal Cognitive Assessment), 1 year after hospital discharge: Early mobilisation 24 (24%) · Usual care 43 (43%)

Association between type II diabetes mellitus and 90-day mortality in a large multicenter prospectively collected cohort. A FROG ICU post-hoc study

2026-10-28T04:33:02.462Z

Secondary analysis · J Crit Care, 2022. 90-day mortality, propensity score (PS)-matched, 90 days — T2DM vs no T2DM: HR 0.81 (CI 0.56-1.18); not significantly different after PS matching

Differences in long-term outcomes between ICU patients with persistent delirium, non-persistent delirium and no delirium: A longitudinal cohort study

2026-10-28T04:33:02.462Z

Cohort study · J Crit Care, 2023. Physical, mental and cognitive outcomes (questionnaires on health, frailty and QoL), 1-year post-ICU — PD: aOR 3.90 (95% CI 1.31-11.63); long-term cognitive impairment; only significant association after adjustment

Institution-free days after critical illness: A multicenter retrospective study

2026-10-28T04:33:02.462Z

Cohort study · J Crit Care, 2023. Distribution of IFD: IFD density distribution bimodal, peak at 0 days and variable right-sided peak depending on definition

Isolated diastolic dysfunction is associated with increased mortality in critically ill patients

2026-10-28T04:33:02.462Z

Secondary analysis · J Crit Care, 2023. Risk of death, 90 days — Indeterminate diastolic function vs Normal diastolic function: OR 4.3 (CI 1.6-11.4); p = 0.004; risk-adjusted

Lower mean phosphate independently predicts mortality in critically ill patients: Results from a prospective cohort study

2026-10-28T04:33:02.462Z

Cohort study · J Crit Care, 2023. ICU and in-hospital mortality, independent predictors (multivariate) — Lower mean phosphate: RR 0.02 (95% CI 0.001-0.09); p = 0.044

Non-pharmacological interventions for self-management of fatigue in adults: An umbrella review of potential interventions to support patients recovering from critical illness

2026-10-28T04:33:02.462Z

Research article · J Crit Care, 2023. Effectiveness of self-management interventions for fatigue: Reviews on cancer 8

Post-traumatic stress disorder and quality of life alterations in survivors of immune-mediated thrombotic thrombocytopenic purpura and atypical hemolytic and uremic syndrome

2026-10-28T04:33:02.462Z

Cross-sectional study · J Crit Care, 2023. Symptoms of anxiety, PTSD and depression: Anxiety symptoms 50%

Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients – A randomized controlled trial

2026-10-28T04:33:02.462Z

Randomised controlled trial · J Crit Care, 2023. Sedation quality: Sedation quality comparable between sevoflurane and propofol

Stakeholder engagement as a strategy to enhance palliative care involvement in intensive care units: A theory of change approach

2026-10-28T04:33:02.462Z

Research article · J Crit Care, 2023. Theory of change map for palliative care integration in ICUs: Desired impact: good death

Critically ill patient mortality by age: long-term follow-up (CIMbA-LT)

2026-10-28T04:30:32.433Z

Cohort study · Ann Intensive Care, 2023. Mortality, all patients: ICU all-cause mortality 16.1%

Accuracy of a Risk Alert Threshold for ICU Hypoglycemia: Retrospective Analysis of Alert Performance and Association With Clinical Deterioration Events

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2022. Level 1 hypoglycemia correctly predicted, ≥1 and ≤12 hours after alert: Hypoglycemia risk alert 48; PPV 13.7%

Age Moderates the Effect of Obesity on Mortality Risk in Critically Ill Patients With COVID-19: A Nationwide Observational Cohort Study*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. Hospital mortality by age subgroup — BMI ≥30 kg/m2 vs BMI <30 kg/m2: aOR 0.59 (95% CI 0.36-0.96); p = 0.03; age <45 yr

Association Between Preexisting Mental Health Disorders and Adverse Outcomes in Adult Intensive Care Patients: A Data Linkage Study

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. Prevalence of documented preexisting mental health disorder: Preexisting mental health disorder 5,044 (31.1%)

Association Between Socioeconomic Status and Outcomes in Critical Care: A Systematic Review and Meta-Analysis

2026-10-28T04:21:38.918Z

Meta-analysis · Crit Care Med, 2022. Mortality, ≤30 days following critical care admission — Lower socioeconomic status vs Higher socioeconomic status: OR 1.13 (95% CI 1.05-1.22); 23 studies; random-effects pooled

Association of Sublingual Microcirculation Parameters and Capillary Refill Time in the Early Phase of ICU Admission*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. Correlation of CRT with microcirculation parameters: MFI, r -0.4430 (p < 0.001)

Deep Learning–Based Recurrent Delirium Prediction in Critically Ill Patients

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. Delirium prediction, 0-12-hour horizon (hold-out test set), 0-12 hr: GRU model: sensitivity 0.810; specificity 0.848; precision (PPV) 0.704; AUROC 0.909

Development and External Validation of a Prediction Model for Quality of Life of ICU Survivors: A Subanalysis of the MONITOR-IC Prospective Cohort Study*

2026-10-28T04:21:38.918Z

Diagnostic or prognostic study · Crit Care Med, 2023. Explained variance of change in quality of life: Full model (49 variables), R2 56.6%

External Validation of Mortality Prediction Models for Critical Illness Reveals Preserved Discrimination but Poor Calibration

2026-10-28T04:21:38.918Z

Diagnostic or prognostic study · Crit Care Med, 2022. Model performance on external validation: Models that could be externally validated 11 (26%)

Immune Profiling Panel Gene Set Identifies Critically Ill Patients With Low Monocyte Human Leukocyte Antigen-DR Expression: Preliminary Results From the REAnimation Low Immune Status Marker (REALISM) Study

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. Identification of immunosuppressed patients: IPP: AUC 0.86 (95% CI 0.83-0.89)

Improving ICU Risk Predictive Models Through Automation Designed for Resiliency Against Documentation Bias

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2022. ICU mortality discrimination: CCOPM 0.925; AUROC 0.925 · APACHE IVa/IVb 0.88; AUROC 0.88

Long-Term Outcome of Severe Metabolic Acidemia in ICU Patients, a BICAR-ICU Trial Post Hoc Analysis

2026-10-28T04:21:38.918Z

Secondary analysis · Crit Care Med, 2022. HRQoL: HRQoL reduced, no significant difference between the two groups

Long-Term Prognosis Following Early Rehabilitation in the ICU: A Retrospective Cohort Study

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. Outpatient consultations: no difference 1 year after discharge; differences between groups 3 years after discharge

Mortality As a Measure of Treatment Effect in Clinical Trials Recruiting Critically Ill Patients*

2026-10-28T04:21:38.918Z

Meta-analysis · Crit Care Med, 2023. Performance characteristics of all-cause mortality endpoint: temporal course, responsiveness to differential treatment effects, impact on practice: Deaths by 180 days that had occurred by day 7 one third

Predicting Readmission or Death After Discharge From the ICU: External Validation and Retraining of a Machine Learning Model

2026-10-28T04:21:38.918Z

Diagnostic or prognostic study · Crit Care Med, 2022. Model performance (discrimination, AUC): External validation: AUC 0.72 (95% CI 0.67-0.76) · Final validation model: AUC 0.79 (95% CI 0.75-0.82)

Routine Versus On-Demand Blood Sampling in Critically Ill Patients: A Systematic Review*

2026-10-28T04:21:38.918Z

Meta-analysis · Crit Care Med, 2023. Exposure to routine blood testing (proportion of patients): Exposure to routine blood testing 52-100%

Safety Outcomes of Direct Discharge Home From ICUs: An Updated Systematic Review and Meta-Analysis (Direct From ICU Sent Home Study)*

2026-10-28T04:21:38.918Z

Meta-analysis · Crit Care Med, 2022. Safety outcomes: readmissions, ED visits and mortality

Subjective Ratings of Mental and Physical Health Correlate With EQ-5D-5L Index Values in Survivors of Critical Illness: A Construct Validity Study*

2026-10-28T04:21:38.918Z

Secondary analysis · Crit Care Med, 2023. Prediction of EQ-5D-5L index value: Two-item regression: nRMSE 0.164; nMAE 0.118; R2adj 0.43 · EQ-5D Visual Analog Scale: nRMSE 0.175; nMAE 0.124; R2adj 0.35 · Stepwise regression with additional covariates: nRMSE 0.133; nMAE 0.1; R2adj 0.51

The Impact of Thoracic Ultrasound on Clinical Management of Critically Ill Patients (UltraMan): An International Prospective Observational Study*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2022. Change of management: TUS 39%

Trajectories of Palliative Care Needs in the ICU and Long-Term Psychological Distress Symptoms*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2022. NEST score: Median NEST score at baseline 22 (IQR, 12-40)

Ultrasound-Guided Infraclavicular Axillary Vein Versus Internal Jugular Vein Cannulation in Critically Ill Mechanically Ventilated Patients: A Randomized Trial

2026-10-28T04:21:38.918Z

Randomised controlled trial · Crit Care Med, 2022. Venipuncture (puncture) success rate: IJV 100% · AXV 99.7%

Association of early mobility with the incidence of deep-vein thrombosis and mortality among critically ill patients: a post hoc analysis of PREVENT trial

2026-10-28T04:14:48.087Z

Secondary analysis · Crit Care, 2023. Incident proximal lower-limb DVT: 4-7 1 (1.3%) · 1-3 7 (2.0%) · 0 50 (4.1%)

Clinician perceptions of the impact of ICU family visiting restrictions during the COVID-19 pandemic: an international investigation

2026-10-28T04:14:48.087Z

Research article · Crit Care, 2023. Themes: Emergence of new technologies

Clustering of critically ill patients using an individualized learning approach enables dose optimization of mobilization in the ICU

2026-10-28T04:14:48.087Z

Secondary analysis · Crit Care, 2023. Likelihood of discharge home by cluster and mobilization parameter — Early mobilization (< 72 h): ORadj 10.0 (CI 2.8 to 44.0); p < 0.001; "Young Trauma" cluster

Focused liquid ultrasonography in dropsy protocol for quantitative assessment of subcutaneous edema

2026-10-28T04:14:48.087Z

Diagnostic or prognostic study · Crit Care, 2023. Subcutaneous edema detected (per measurement): Ultrasound 522 (36.3%) · Pitting test 444 (30.8%)

Incidence of near-death experiences in patients surviving a prolonged critical illness and their long-term impact: a prospective observational study

2026-10-28T04:14:48.087Z

Cohort study · Crit Care, 2023. NDE incidence (Greyson NDE scale cut-off score ≥ 7/32), first 7 days after discharge: Patients reporting NDE, of 126 included 19 (15%)

Limitation of life-sustaining therapies in critically ill patients with COVID-19: a descriptive epidemiological investigation from the COVID-ICU study

2026-10-28T04:14:48.087Z

Cohort study · Crit Care, 2023. In-ICU LST limitations: Prevalence of in-ICU LST limitations 14.5%

Outcomes in critically Ill HIV-infected patients between 1997 and 2020: analysis of the OUTCOMEREA multicenter cohort

2026-10-28T04:14:48.087Z

Cohort study · Crit Care, 2023. Patient profile over time: Mean age and number of comorbidities (diabetes, renal and respiratory history, solid neoplasia) increased over time

Prevalence of long-term decision regret and associated risk factors in a large cohort of ICU surrogate decision makers

2026-10-28T04:14:48.087Z

Secondary analysis · Crit Care, 2023. Decision Regret Scale score, 6 months: DRS score, median (IQR) 15 (0, 25)

The rate and assessment of muscle wasting during critical illness: a systematic review and meta-analysis

2026-10-28T04:14:48.087Z

Meta-analysis · Crit Care, 2023. Daily muscle loss during first week, first week of critical illness: Daily loss of rectus femoris thickness -1.75% (95% CI -2.05, -1.45)

Association between acute disease severity and one-year quality of life among post-hospitalisation COVID-19 patients: Coalition VII prospective cohort study

2026-10-28T04:13:06.971Z

Cohort study · Intensive Care Med, 2023. EQ-5D-3L utility score, 1 year: Severity score 5 0.7 · Severity score 2 0.84

Haloperidol vs. placebo for the treatment of delirium in ICU patients: a pre-planned, secondary Bayesian analysis of the AID–ICU trial

2026-10-28T04:13:06.971Z

Secondary analysis · Intensive Care Med, 2023. Days alive and out of hospital, up to day 90: Mean difference, haloperidol vs placebo 2.9 days (95% CrI - 1.1 to 6.9) (95% CrI)

Validation of the patient State Index for monitoring sedation state in critically ill patients: a prospective observational study

2026-10-28T04:08:44.882Z

Cohort study · J Clin Monit Comput, 2022. Correlation between PSI and RASS: Spearman's rank correlation coefficient, PSI vs RASS 0.79 (95% CI 0.75-0.83)

Association between neuromuscular blocking agents and the development of intensive care unit-acquired weakness (ICU-AW): A systematic review with meta-analysis and trial sequential analysis

2026-10-28T03:54:35.559Z

Meta-analysis · Anaesth Crit Care Pain Med, 2023. Development of ICU-AW — NMBA vs No NMBA: OR 2.77 (95% CI 1.98-3.88); I2 = 62%

Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis

2026-10-28T03:51:30.684Z

Meta-analysis · Can J Anaesth, 2023. Sleep quality measured using a VAS — Melatonin vs Placebo: mean difference -0.75 mm (95% CI -4.86 to 3.35); I2, 5%