CurrentAnesthesia — Neuroanesthesia & neurocritical care

Review Paper on Penetrating Brain Injury: Ethical Quandaries in the Trauma Bay and Beyond

2026-10-28T04:46:28.518Z

Guideline or statement · Ann Surg, 2022. Traditional TBI prognostic signs may not be applicable to PBI; multidisciplinary team approach suggested case by case

Trends in Intensive Care Admissions and Outcomes of Stroke Patients Over 10 Years in Brazil: Impact of the COVID-19 Pandemic

2026-10-28T04:40:50.491Z

Cohort study · Chest, 2022. In-hospital mortality: Ischemic stroke 9% · Hemorrhagic stroke 24%

Electroencephalography for prognostication of outcome in adults with severe herpes simplex encephalitis

2026-10-28T04:30:32.433Z

Cohort study · Ann Intensive Care, 2023. Poor functional outcome (modified Rankin Scale (mRS) 3 to 6) at 90 days, by absence of stdEEG reactivity — Absence of reactivity: OR 2.80 (95% CI 1.19 to 6.58); whole population

Acute Effects of Ketamine on Intracranial Pressure in Children With Severe Traumatic Brain Injury*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. ICP and CPP after ketamine bolus vs baseline: Sedation doses: no significant difference in ICP or CPP from baseline

Electrocardiographic Changes at the Early Stage of Status Epilepticus: First Insights From the ICTAL Registry*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2022. Early ECG abnormalities: Any early ECG abnormality 145 (93.5%)

Hemoglobin Concentration Impacts Viscoelastic Hemostatic Assays in ICU Admitted Patients*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. Correlation of hemoglobin with viscoelastic parameters: ROTEM ICH: r, coagulation kinetics 0.46; p, coagulation kinetics p = 0.01; r, clot strength -0.52; p, clot strength p = 0.002 · TEG ICH: r, coagulation kinetics 0.49; p, coagulation kinetics p < 0.0001; r, clot strength -0.40; p, clot strength p < 0.0001

Neuromonitoring in Critically Ill Patients

2026-10-28T04:21:38.918Z

Research article · Crit Care Med, 2023. Numerous neuromonitoring modalities investigated in critically ill patients, monitoring clinical neurologic assessments, electrophysiology, cerebral blood flow, substrate delivery and utilization, and cellular metabolism

Impact of continuous hypertonic (NaCl 20%) saline solution on renal outcomes after traumatic brain injury (TBI): a post hoc analysis of the COBI trial

2026-10-28T04:14:48.087Z

Secondary analysis · Crit Care, 2023. AKI, 28 days: Intervention 24.5% · Control 28.9%

Neurological and respiratory effects of lung protective ventilation in acute brain injury patients without lung injury: brain vent, a single centre randomized interventional study

2026-10-28T04:14:48.087Z

Randomized controlled trial · Crit Care, 2023. ICP change from baseline (patients without intervention interruption): low VT/low PEEP 2.2 mmHg · low VT/high PEEP 2.3 mmHg

Severity scores for status epilepticus in the ICU: systemic illness also matters

2026-10-28T04:14:48.087Z

Cohort study · Crit Care, 2023. In-hospital death (AUC): STESS: AUC 0.58 · EMSE: AUC 0.69 · APACHE-2: AUC 0.72 · SAPS-2: AUC 0.73 · SOFA: AUC 0.71

Cerebro-spinal fluid glucose and lactate concentrations changes in response to therapies in patIents with primary brain injury: the START-TRIP study

2026-10-28T04:14:48.087Z

Cohort study · Crit Care, 2023. Change in CGLR, 2 h after intervention: Intervention 20.2% · Control 1.6%

Temporal trends in mortality and provision of intensive care in younger women and men with acute myocardial infarction or stroke

2026-10-28T04:14:48.087Z

Cohort study · Crit Care, 2023. Sex-specific temporal trends in ICU admission and ICU mortality, AMI and stroke, 2008–2019: Women - 6.4%; Change in ICU admissions for AMI over 12 years - 6.4% · Men - 4.5%; Change in ICU admissions for AMI over 12 years - 4.5%

Valproic acid as adjuvant treatment for convulsive status epilepticus: a randomised clinical trial

2026-10-28T04:14:48.087Z

Randomized controlled trial · Crit Care, 2023. Proportion of patients discharged from hospital by day 15, day 15: VPA 77 (61%) · Placebo 72 (61%)

Treatments for intracranial hypertension in acute brain-injured patients: grading, timing, and association with outcome. Data from the SYNAPSE-ICU study

2026-10-28T04:13:06.971Z

Secondary analysis · Intensive Care Med, 2023. Mortality, six months — No-basic TIL vs eTIL: HR 1.612 (95% CI 1.243-2.091); p < 0.001

Feasibility and optimal choice of stimulation parameters for supramaximal stimulation of motor evoked potentials

2026-10-28T04:08:44.882Z

Cohort study · J Clin Monit Comput, 2023. Supramaximal stimulation achieved: Setting 1 38 · Setting 2 26 (68.42%)

Higher intracranial pressure variability is associated with lower cerebrovascular resistance in aneurysmal subarachnoid hemorrhage

2026-10-28T04:08:44.882Z

Cohort study · J Clin Monit Comput, 2022. Association of ICPV with CVR and CBF, Vasospasm phase (days 4-14): Higher ICPV-4h independently associated with lower CVR (multiple linear regression), β - 0.19, p < 0.05

Intradural extramedullary tumor location in the axial view affects the alert timing of intraoperative neurophysiologic monitoring

2026-10-28T04:08:44.882Z

Cohort study · J Clin Monit Comput, 2023. Monitoring accuracy of IONM alerts: False-positive cases 11

Unexpected median SEPs fluctuations during brain cavernous malformation resection with no post-operative deficit

2026-10-28T04:08:44.882Z

Cohort study · J Clin Monit Comput, 2022. Intraoperative m-SEP changes and post-operative deficits: All patients presented m-SEPs alterations on the side of the lesion during the procedure

Zero-heat-flux thermometry over the carotid artery in assessment of core temperature in craniotomy patients

2026-10-28T04:08:44.882Z

Research article · J Clin Monit Comput, 2023. Bland-Altman agreement with esophageal temperature, entire anesthesia: ZHF-neck mean 0.1 (limits of agreement -0.7 to +0.8) °C · ZHF-forehead mean 0.0 (limits of agreement -0.8 to +0.8) °C

Anaesthetic and peri-operative management for thrombectomy procedures in stroke patients

2026-10-28T03:54:35.559Z

Guideline or statement · Anaesth Crit Care Pain Med, 2023.

Impact of hyperoxia and phenylephrine on cerebral oxygenation: An experimental clinical study

2026-10-28T03:44:37.230Z

Mechanistic study · Acta Anaesthesiol Scand, 2022. PbtO2: 30% oxygen median 22 (5%-95% range 4.6-54) mmHg · 80% oxygen median 68 (5%-95% range 8.4-99) mmHg · Before phenylephrine median 21 (5%-95% range 4.5-81) mmHg · After phenylephrine median 19 (5%-95% range 4.2-56) mmHg

Comparative effectiveness of anesthetic technique on outcomes after lumbar spine surgery: a retrospective propensity score-matched analysis of the National Surgical Quality Improvement Program, 2009–2019

2026-10-28T03:38:31.027Z

Cohort study · Reg Anesth Pain Med, 2023. Any complication — RA vs GA: OR 0.43 (95% CI 0.3 to 0.6); p<0.001; unadjusted

Dynamic cerebral autoregulation during step-wise increases in blood pressure during anaesthesia: A nonrandomised interventional trial

2026-10-28T03:35:32.861Z

Research article · Eur J Anaesthesiol, 2023. Change in dynamic CA (phase lead) per mmHg MAP: Propofol 0.73 (95% CI 0.51 to 0.95) ° mmHg -1; P P ≤ 0.001 · Sevoflurane 0.21 (95% CI 0.01 to 0.42) ° mmHg -1; P P = 0.04

The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline

2026-10-28T03:25:23.999Z

Guideline or statement · Anaesthesia, 2023.

Dexmedetomidine administration during brain tumour resection for prevention of postoperative delirium: a randomised trial

2026-10-28T03:18:44.786Z

Randomized controlled trial · Br J Anaesth, 2022. Incidence of delirium (Confusion Assessment Method twice daily), initial 5 postoperative days: Dexmedetomidine 28 (22%) · Placebo 60 (46%)

Perioperative ischaemic brain injury and plasma neurofilament light: a secondary analysis of two prospective cohort studies

2026-10-28T03:18:44.786Z

Secondary analysis · Br J Anaesth, 2022. Incidence of covert stroke (preoperative) and ischaemic brain injury (postoperative): Preoperative 2 (2% (Bayesian 95% CI 0.2-5.4)) · Postoperative 7 (12% (Bayesian 95% CI 4.9-21.3%))

Quantitative analysis of early-stage EEG reactivity predicts awakening and recovery of consciousness in patients with severe brain injury

2026-10-28T03:18:44.786Z

Cohort study · Br J Anaesth, 2022. Awakening in the ICU — Variation in delta-band phase-lag index connectivity after noise stimulation: aOR 0.89 (95% CI 0.81-0.97); P=0.02; corrected for multiple tests; adjusted for age, baseline severity, and sedation

Preoperative β-Blocker Therapy and Stroke or Major Adverse Cardiac Events in Major Abdominal Surgery: A Retrospective Cohort Study

2026-10-28T03:16:58.759Z

Cohort study · Anesthesiology, 2022. In-hospital stroke: β-blocker initiation 17 (0.4%) · Chronic β-blocker 171 (0.4%) · β-blocker-naïve 235 (0.2%)

Identification of Palliative Care Needs and Mental Health Outcomes Among Family Members of Patients With Severe Acute Brain Injury

2026-10-27T23:37:19.358Z

Cohort study · JAMA Netw Open, 2023. Palliative care needs identified and family psychological symptoms: At least 1 need identified by family members 185 (88%)

Early tracheostomy in patients undergoing mechanical thrombectomy for acute ischemic stroke

2026-10-27T23:28:00.394Z

Cohort study · J Crit Care, 2023. length of stay (LOS) and total hospital charges — ETR vs Later tracheostomy: LOS 25.39 days vs 32.43 days days; p < 0.001

Factors associated with acute respiratory distress syndrome in brain-injured patients: A systematic review and meta-analysis

2026-10-27T23:28:00.394Z

Meta-analysis · J Crit Care, 2023. Factors associated with ARDS (adjusted analysis) — Sepsis: OR 4.38 (95% CI 2.37-8.10); high certainty

The predictive value of EEG reactivity by electrical stimulation and quantitative analysis in critically ill patients with large hemispheric infarction

2026-10-27T23:28:00.394Z

Diagnostic or prognostic study · J Crit Care, 2023. Good outcome prediction, within 6-month: Pain, visual: AUC 0.763 · Pain, quantitative: AUC 0.844 · Electrical, visual: AUC 0.825 · Electrical, quantitative: AUC 0.931

Clinical and Electroencephalographic Predictors of Seizures and Status Epilepticus in 12,450 Critically Ill Adults: A Retrospective Cohort Study

2026-10-27T23:20:28.165Z

Cohort study · Crit Care Med, 2023. Factors independently associated with SE (% with SE; aOR [CI]), first 72 hours of cEEG: AnySz (isolated seizures or SE) 1,226 patients (9.8%)

State-of-the-Art Evaluation of Acute Adult Disorders of Consciousness for the General Intensivist

2026-10-27T23:20:28.165Z

Research article · Crit Care Med, 2023. Acute adult DoC may be categorised by etiology (structural, functional, infectious, inflammatory, pharmacologic), which drives diagnostic investigation, monitoring, acute therapy and specialist care decisions incl. team-based local care and intra- and inter-facility transfer

Effect of propranolol and clonidine after severe traumatic brain injury: a pilot randomized clinical trial

2026-10-27T23:14:23.345Z

Randomized controlled trial · Crit Care, 2023. VFDs, 28 days — Treatment vs Placebo: difference 0.3 days (95% CI - 5.4, 5.8); p = 1.0; no significant difference

The lower limit of reactivity as a potential individualised cerebral perfusion pressure target in traumatic brain injury: a CENTER-TBI high-resolution sub-study analysis

2026-10-27T23:14:23.345Z

Secondary analysis · Crit Care, 2023. Prediction of mortality by %time with CPP < LLR, first 7 days: AUC of %time with CPP < LLR for mortality 0.73

Mechanical ventilation in patients with acute brain injury: a systematic review with meta-analysis

2026-10-27T23:14:23.345Z

Meta-analysis · Crit Care, 2023. Mortality — Low tidal volume vs High tidal volume: OR 0.88 (95% CI 0.74 to 1.05); p = 0.16; I2 = 20%

Modifications of lung microbiota structure in traumatic brain injury ventilated patients according to time and enteral feeding formulas: a prospective randomized study

2026-10-27T23:14:23.345Z

Randomized controlled trial · Crit Care, 2023. Lung microbiota beta diversity by nutrition: Specialized nutrition influenced beta diversity, statistically significant only in Bray-Curtis distance

The oxygen reactivity index indicates disturbed local perfusion regulation after aneurysmal subarachnoid hemorrhage: an observational cohort study

2026-10-27T23:14:23.345Z

Cohort study · Crit Care, 2023. Mean ORx and PRx by probe location: DCI + /probe + mean 0.28 ± 0.13; PRx 0.12 ± 0.17 · DCI + /probe- mean 0.18 ± 0.15; PRx 0.06 ± 0.20 · DCI- mean 0.20 ± 0.14; PRx 0.08 ± 0.17

Tracheostomy timing and outcome in critically ill patients with stroke: a meta-analysis and meta-regression

2026-10-27T23:14:23.345Z

Meta-analysis · Crit Care, 2023. All-cause overall mortality: Early 7.8% · Late 16.4%

Utilization of mechanical power and associations with clinical outcomes in brain injured patients: a secondary analysis of the extubation strategies in neuro-intensive care unit patients and associations with outcome (ENIO) trial

2026-10-27T23:14:23.345Z

Secondary analysis · Crit Care, 2023. MP and clinical outcomes (adjusted relative risk (aRR) at 17 J/min vs HD1 median MP 11.9 J/min): Median MP on HD1, J/min [IQR 9.2-15.1] 11.9

Acute traumatic coma awakening by right median nerve electrical stimulation: a randomised controlled trial

2026-10-27T23:13:02.241Z

Randomized controlled trial · Intensive Care Med, 2023. Proportion of patients who regained consciousness, 6 months post-injury: RMNS 121 (72.5% (95% CI 65.2-78.7%)) · Control 92 (56.8% (95% CI 49.1-64.2%))

Association between prehospital end-tidal carbon dioxide levels and mortality in patients with suspected severe traumatic brain injury

2026-10-27T23:13:02.241Z

Cohort study · Intensive Care Med, 2023. 30-day mortality by end-tidal CO2, 30 days — < 35 mmHg: OR 1.89 (95% CI 1.53-2.34); p < 0.001; hypocapnia

Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study

2026-10-27T23:13:02.241Z

Cohort study · Intensive Care Med, 2023. Poor functional outcome, 3 months: Poor functional outcome, all patients 298 (50.5%, 95% CI 46.6-54.6%)

Are NIRS-derived cerebral autoregulation and ABPopt values different between hemispheres in hypoxic-ischemic brain injury patients following cardiac arrest?

2026-10-27T23:08:04.173Z

Cohort study · J Clin Monit Comput, 2023. ABPopt, left vs right NIRS recordings: Left 80 (95% CI 76-84) mmHg · Right 82 (95% CI 75-84) mmHg

Neural networks for estimation of facial palsy after vestibular schwannoma surgery

2026-10-27T23:08:04.173Z

Research article · J Clin Monit Comput, 2022. Estimation of postoperative HB grades (chi2): Traintime + preoperative HB + tumor size chi2 54.8 · Tumor size chi2 30.6 · Mean traintime chi2 31.9

Noninvasive intracranial pressure waveforms for estimation of intracranial hypertension and outcome prediction in acute brain-injured patients

2026-10-27T23:08:04.173Z

Cohort study · J Clin Monit Comput, 2022. Correlation of Mean ICP (mICP) and P2/P1; P2/P1 for intracranial hypertension (IHT) (ICP > 20 mmHg): Correlation mICP vs P2/P1 (r) 0.49, p < 0.001

Predictor role of heart rate variability in subarachnoid hemorrhage: A systematic review

2026-10-27T23:08:04.173Z

Meta-analysis · J Clin Monit Comput, 2023. Early heart rate variability (HRV) changes and complications/outcome: Early changes in HRV indices (time and frequency domain) correlated with neuro-cardiogenic complications and poor neurologic outcome in SAH

Preoperative assessment of optic nerve sheath diameter and heart rate variability to predict intraoperative brain condition in patients with supratentorial tumors: a prospective observational study

2026-10-27T23:08:04.173Z

Cohort study · J Clin Monit Comput, 2022. Predictors of intraoperative brain bulge (ROC cut-offs): Significant difference in CT grade, ONSD and HRV parameters between lax and tight brain

Quantitative regional cerebral blood flow measurement using near-infrared spectroscopy and indocyanine green in patients undergoing superficial temporal to middle cerebral artery bypass for moyamoya disease: a novel method using a frequency filter

2026-10-27T23:08:04.173Z

Diagnostic or prognostic study · J Clin Monit Comput, 2022. Agreement rCBF_N vs rCBF_S (ICC3): ICC3, diseased side (weak); 95% CI -0.03-0.5; p = 0.07 0.25