CurrentAnesthesia — Pain medicine

Regional analgesic techniques for postoperative pain after kidney transplantation: a systematic review and Bayesian meta-analysis

2026-10-28T10:36:56.498Z

Meta-analysis · Br J Anaesth, 2026.

Enhanced Recovery After Surgery Patients Are Prescribed Fewer Opioids at Discharge: A Propensity-score Matched Analysis

2026-10-28T04:46:28.518Z

Cohort study · Ann Surg, 2023. Discharge opioid pills and oral morphine equivalents (matched): Post-ERAS 17.4 pills; oral morphine equivalents 129.4 mg · Pre-ERAS 22.0 pills; oral morphine equivalents 167.6 mg

Evidence-Based Opioid Prescribing Guidelines and New Persistent Opioid Use After Surgery

2026-10-28T04:46:28.518Z

Research article · Ann Surg, 2023. New persistent opioid use (adjusted incidence): Michigan 2.51% (95% CI 2.35-2.67%); before guidelines 3.29% (95% CI 3.15-3.43%)

Prospective Evaluation of a Tiered Opioid Prescribing Guideline for Inpatient Colorectal Operations

2026-10-28T04:46:28.518Z

Cohort study · Ann Surg, 2021. Opioid prescribing (EOP): Reduction in mean prescription quantity 41%

Reasons for Long-term Opioid Prescriptions After Guideline-directed Opioid Prescribing and Excess Opioid Pill Disposal

2026-10-28T04:46:28.518Z

Secondary analysis · Ann Surg, 2021. Long-term opioid rx filled, 3 to 12 months after surgery: Filled an opioid rx 3 to 12 months after surgery 15.3% (34/221)

The Effect of Cryotherapy Application on Postoperative Pain: A Systematic Review and Meta-analysis

2026-10-28T04:46:28.518Z

Meta-analysis · Ann Surg, 2023. Postoperative pain — Cryotherapy vs No cryotherapy: SMD -0.50 (95% CI -0.71 to -0.29); POD 1; I² = 74%

Comparison of Opioids Prescribed by Advanced Practice Clinicians vs Surgeons After Surgical Procedures in the US

2026-10-28T04:44:26.953Z

Cross-sectional study · JAMA Netw Open, 2023. Prescriptions written by APCs: Perioperative opioid prescriptions written by APCs (119 266 of 628 197) 19.0%

Evaluation of machine learning models as decision aids for anesthesiologists

2026-10-28T04:08:44.882Z

Research article · J Clin Monit Comput, 2022. Accuracy of peak glucose estimates: Without ML assistance 79.0% (± 13.7%) % · With ML assistance 84.7% (± 11.5%) %

Prediction of acute postoperative pain based on intraoperative nociception level (NOL) index values: the impact of machine learning-based analysis

2026-10-28T04:08:44.882Z

Secondary analysis · J Clin Monit Comput, 2022. Prediction of moderate to severe postoperative pain, best algorithm: Penalized logistic regression CV-AUC (best performance) 0.753 (0.718-0.788)

Benefit of epidural analgesia for postoperative pain control after a Kasai Portoenterostomy: A ten‐year retrospective cohort study

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2022. Total opioid requirement (morphine equivalents), first 72 h: Epidural Mean 0.52 (95% CI 0.38, 0.67) mg/kg · Non-epidural Mean 1.15 (95% CI 0.8, 1.48) mg/kg

Pectoral Fascial Plane Versus Paravertebral Blocks for Minimally Invasive Mitral Valve Surgery Analgesia

2026-10-28T03:56:35.329Z

Cohort study · J Cardiothorac Vasc Anesth, 2023. Postoperative opioid use and pain scores: Significantly fewer opioids in the immediate postoperative period with PECS II vs paravertebral

A Single Preoperative Dose of S-Ketamine Has No Beneficial Effect on Chronic Postsurgical Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgical Lung Lesion Resection: A Prospective Randomized Controlled Study

2026-10-28T03:56:35.329Z

Randomised controlled trial · J Cardiothorac Vasc Anesth, 2023. Incidence of CPSP and neuropathic pain: No significant differences between the 2 groups in the incidences of CPSP and neuropathic pain

Analgesic efficacy of inter-semispinal fascial plane block in Patients undergoing Cervical Spine Surgery through Posterior Approach: a randomized controlled trial

2026-10-28T03:54:35.559Z

Randomised controlled trial · Anaesth Crit Care Pain Med, 2023. Intraoperative fentanyl and 24-h postoperative morphine: ISPB median 175 (range 110-220) μg · Control median 290 (range 110-350) μg · ISPB median 7 (range 5-12) mg · Control median 12 (range 8-21) mg

Erector spinae plane block versus subcostal transversus abdominis plane block in patients undergoing open liver resection surgery: A randomized controlled trial

2026-10-28T03:54:35.559Z

Randomised controlled trial · Anaesth Crit Care Pain Med, 2022. Postoperative morphine consumption, 24 h: ESPB median 20 (quartiles 15-20) mg · Subcostal TAPB median 25 (quartiles 20-30) mg

A prospective observational study of the efficacy of ketamine for rescue analgesia in the postanesthesia recovery unit

2026-10-28T03:51:30.684Z

Cohort study · Can J Anaesth, 2023. Resting NRS pain score reduction, 30 min after iv ketamine: Ketamine mean 2.7 ± 1.8

Use of injections for chronic pain from 2010 to 2019 in Ontario, Canada

2026-10-28T03:51:30.684Z

Cohort study · Can J Anaesth, 2022. Pain injections and associated costs, 2010 to 2019: Total pain injections included 18,050,058

Glucocorticoids added to paracetamol and NSAIDs for post‐operative pain: A systematic review with meta‐analysis and trial sequential analysis

2026-10-28T03:44:37.230Z

Meta-analysis · Acta Anaesthesiol Scand, 2023. Cumulative opioid consumption, 24 h postoperatively — Glucocorticoids vs Placebo/no intervention: MD -0.28 (95% CI -1.90 to 1.33); p = .68; Trial sequential analysis (TSA)-adjusted CI; moderate certainty of evidence

Minimal important difference in opioid consumption based on adverse event reduction—A study protocol

2026-10-28T03:44:37.230Z

Trial design · Acta Anaesthesiol Scand, 2022. Hodges-Lehmann median difference in opioid consumption between patients with no opioid-related adverse effects and those with the mildest degree of ≥1 opioid-related adverse effect

Opioid consumption and non‐opioid multimodal analgesic treatment in pain management trials after hip and knee arthroplasties: A meta‐epidemiological study

2026-10-28T03:44:37.230Z

Research article · Acta Anaesthesiol Scand, 2023. Median 0-24 h opioid consumption: Hip arthroplasty trials median 21 mg iv morphine equivalents · Knee arthroplasty trials median 22 mg iv morphine equivalents

Pain treatment after total hip arthroplasty: Detailed statistical analysis plan for the RECIPE randomised clinical trial

2026-10-28T03:44:37.230Z

Trial design · Acta Anaesthesiol Scand, 2023. Total opioid consumption, 0-24 h after end of surgery

Posterior quadratus lumborum block versus epidural analgesia for postoperative pain management after open radical cystectomy: A randomized clinical trial

2026-10-28T03:44:37.230Z

Randomised controlled trial · Acta Anaesthesiol Scand, 2023. Cumulative rescue opioid consumption, POD 0 (9-12 h): QLB 14 (interval (unspecified) 7.6-33.3) mg; doses 8 (3.6-15.7) · Epidural analgesia 6.1 (interval (unspecified) 2.0-16.1) mg; doses 4 (1.3-8.5)

Repeat dose steroid in high pain responders after total knee arthroplasty: A study protocol

2026-10-28T03:44:37.230Z

Trial design · Acta Anaesthesiol Scand, 2023. Moderate to severe pain (VAS > 30) during a 5 m walk test, morning of Day 2 after surgery

Unresolved early post‐operative pain trajectory predicts moderate‐to‐severe persistent pain after breast cancer surgery—An observational cohort study

2026-10-28T03:44:37.230Z

Cohort study · Acta Anaesthesiol Scand, 2023. Persistent pain after breast cancer surgery (PPBCS): Mild PPBCS 18% (n = 108)

Opioid sparing effects of intravenous and oral acetaminophen in hip fracture patients: A population-based study

2026-10-28T03:40:44.883Z

Cohort study · J Clin Anesth, 2023. Opioid use standardized by hospital LOS — IVAPAP vs APAP: difference 2.8% (CI 2%, 3.6%); p < .001; slightly higher with IVAPAP

Comparison of cooled versus conventional radiofrequency treatment of the genicular nerves for chronic knee pain: a multicenter non-inferiority randomized pilot trial (COCOGEN trial)

2026-10-28T03:38:31.027Z

Randomised controlled trial · Reg Anesth Pain Med, 2023. Proportion of patients with ≥50% pain reduction, 3 months postintervention: Conventional RF 4 (17%) · Cooled RF 8 (33%)

Evidence-based consensus guidelines on patient selection and trial stimulation for spinal cord stimulation therapy for chronic non-cancer pain

2026-10-28T03:38:31.027Z

Guideline or statement · Reg Anesth Pain Med, 2023.

History of abuse is associated with thoughts of harm among patients with pain after accounting for depressive symptoms

2026-10-28T03:38:31.027Z

Cross-sectional study · Reg Anesth Pain Med, 2022. Thoughts of harm by abuse history, stratified by depressive symptoms: Abuse history significantly associated with increased odds of thoughts of harm in patients with moderate to severe depressive symptoms

Impact of the COVID-19 pandemic on opioid overdose and other adverse events in the USA and Canada: a systematic review

2026-10-28T03:38:31.027Z

Meta-analysis · Reg Anesth Pain Med, 2022. Changes in opioid-related outcomes after COVID-19 onset: Opioid-related emergency medicine utilization increased in most studies (85%, 11/13)

Patient-centered results from a multicenter study of continuous peripheral nerve blocks and postamputation phantom and residual limb pain: secondary outcomes from a randomized, clinical trial

2026-10-28T03:38:31.027Z

Secondary analysis · Reg Anesth Pain Med, 2023. ≥2-point NRS improvement in average and worst phantom pain, 4 weeks: Ropivacaine 57% · Saline: average pain 26%; worst pain 25%

Role of patient selection and trial stimulation for spinal cord stimulation therapy for chronic non-cancer pain: a comprehensive narrative review

2026-10-28T03:38:31.027Z

Research article · Reg Anesth Pain Med, 2023. Trial success rate and therapy success, 12 months: RCTs median 72%; therapy success at 12 months 65% · OSs median 82%; therapy success at 12 months 61%

Sarcopenia is associated with an increase in long-term use of analgesics after elective surgery under general anesthesia

2026-10-28T03:38:31.027Z

Cohort study · Reg Anesth Pain Med, 2023. Long-term non-opioid analgesic and opioid use, 3 and 6 months: Sarcopenia 49.7%; 3-month non-opioid analgesic use 49.7%; 3-month opioid use 1.8%; 6-month non-opioid analgesic use 31.6%; 6-month opioid use 1.2% · Non-sarcopenia 37.9%; 3-month non-opioid analgesic use 37.9%; 3-month opioid use 0.9%; 6-month non-opioid analgesic use 17.2%; 6-month opioid use 0.3%

Additive or synergistic analgesic effect of metamizole on standard pain treatment at home after arthroscopic shoulder surgery: A randomised controlled superiority trial

2026-10-28T03:35:32.861Z

Randomised controlled trial · Eur J Anaesthesiol, 2023. Postoperative pain intensity on movement (11-point NRS, 0 = no pain, 10 = worst pain imaginable), POD 1 — MIP vs i.p.: mean difference -0.08 NRS (95% CI -1.00 to 0.84); superiority of MIP not confirmed

Less use of rescue morphine when a combined PSP/IPP-block is used for postoperative analgesia in breast cancer surgery: A randomised controlled trial

2026-10-28T03:35:32.861Z

Randomised controlled trial · Eur J Anaesthesiol, 2023. Cumulative IV rescue morphine to reach pain control (VAS <40 mm), first 48 h after surgery: Intervention median 2.25 mg · Control median 3.0 mg

Systemic glucocorticoids as an adjunct to treatment of postoperative pain after total hip and knee arthroplasty: A systematic review with meta-analysis and trial sequential analysis

2026-10-28T03:35:32.861Z

Meta-analysis · Eur J Anaesthesiol, 2022. IV morphine (or equivalent) consumption (MID 5 mg), 24 h — Glucocorticoid vs Placebo or no intervention: reduction 5.0 mg (95% CI 2.2 to 7.7); P = 0.0004

Appropriate Duration of Perioperative Intravenous Administration of Lidocaine to Provide Satisfactory Analgesia for Adult Patients Undergoing Colorectal Surgery: A Meta-Analysis of Randomized Controlled Trials

2026-10-28T03:28:59.708Z

Meta-analysis · Anesth Analg, 2023. Pain scores (VAS, 0-10 cm) at rest and on movement, 24 hours postoperatively — Prolonged lidocaine infusion vs Placebo: MD -0.91 cm (95% CI -1.54 to -0.28); P = .02; at rest

The Effect of Intrathecal Morphine on Postoperative Opioid Consumption in Patients Undergoing Abdominal Surgery for Gynecologic Malignancy: A Randomized Sham-Controlled Trial

2026-10-28T03:28:59.708Z

Randomised controlled trial · Anesth Analg, 2023. Cumulative IV opioid consumption, 24 hours after surgery: ITM median 18 (IQR 12-29) mg · Sham median 36 (IQR 27-42) mg

Nociception Level Index–Guided Intraoperative Analgesia for Improved Postoperative Recovery: A Randomized Trial

2026-10-28T03:28:59.708Z

Randomised controlled trial · Anesth Analg, 2023. Pain score, first 60 minutes after awakening: NOL mean 4.12 ± 0.59 · Routine care mean 4.04 ± 0.58

A randomised controlled trial of the analgesia nociception index for intra‐operative remifentanil dose and pain after gynaecological laparotomy

2026-10-28T03:25:23.999Z

Randomised controlled trial · Anaesthesia, 2023. Pain scores ≥ 5 (scale 0-10) within 40 min of admission to recovery — Analgesia nociception index vs SBP; p = 0.73

Feasibility of virtual reality‐delivered pain psychology therapy for cancer‐related neuropathic pain: a pilot randomised controlled trial

2026-10-28T03:25:23.999Z

Randomised controlled trial · Anaesthesia, 2023. Feasibility, acceptability, recruitment and cybersickness: Recruited of eligible 47%

Incidence of persistent postoperative opioid use in patients undergoing ambulatory surgery: a retrospective cohort study

2026-10-28T03:25:23.999Z

Cohort study · Anaesthesia, 2022. Persistent postoperative opioid use: Incidence of persistent postoperative opioid use: 44,224 patients, 95% CI 12.9-13.1% 13.0%

Network meta‐analysis of the analgesic effectiveness of regional anaesthesia techniques for anterior cruciate ligament reconstruction

2026-10-28T03:25:23.999Z

Meta-analysis · Anaesthesia, 2022. Opioid consumption, first 24 h: All regional anaesthesia techniques superior to systemic analgesia alone

Risk factors for persistent pain after breast cancer surgery: a multicentre prospective cohort study

2026-10-28T03:25:23.999Z

Cohort study · Anaesthesia, 2023. Persistent pain incidence and independent risk factors (multivariable model), 4 months after surgery: Persistent pain 135 (64.3%)

Supraneural versus Infraneural Approach to transforaMinal Epidural StEroid injection for unilateral lumbosacral radicular pain (SIAMESE): a study protocol for a randomised non-inferiority trial

2026-10-28T03:24:27.424Z

Trial design · BJA Open, 2023. Differential impact on pain intensity score, 3 months

Effect of transauricular nerve stimulation on perioperative pain: a single-blind, analyser-masked, randomised controlled trial

2026-10-28T03:18:44.786Z

Randomised controlled trial · Br J Anaesth, 2023. Reduction in VAS, 24 h postoperatively: Active TAN mean 19 (95% CI 12-26) mm · Sham TAN mean 10 (95% CI 3-17) mm

Neuroimaging reveals a potential brain-based pre-existing mechanism that confers vulnerability to development of chronic painful chemotherapy-induced peripheral neuropathy

2026-10-28T03:18:44.786Z

Cohort study · Br J Anaesth, 2022. Brain responses to punctate stimulation: Group contrast: CIPN+ vs CIPN- had robust activity in sensory, motor, attentional and affective brain regions

Out-of-hospital opioid prescriptions after knee and hip arthroplasty: prescribers and the first prescribed opioid

2026-10-28T03:18:44.786Z

Cohort study · Br J Anaesth, 2023. Opioid prescription (≥1 opioid): KA 70% · HA 51%

Phenotype- and species-specific skin proteomic signatures for incision-induced pain in humans and mice

2026-10-28T03:18:44.786Z

Mechanistic study · Br J Anaesth, 2023. Skin protein regulation and PPI, 24 h after incision: Regulated proteins in human skin 119/1569

Towards precision pain medicine for pain after cancer: the Cancer Pain Phenotyping Network multidisciplinary international guidelines for pain phenotyping using nociplastic pain criteria

2026-10-28T03:18:44.786Z

Guideline or statement · Br J Anaesth, 2023.

Validation of three nociception indices to predict immediate postoperative pain before emergence from general anaesthesia: a prospective double-blind, observational study

2026-10-28T03:18:44.786Z

Diagnostic or prognostic study · Br J Anaesth, 2023. Moderate-to-severe postoperative pain: HR: AUC 0.46 [0.29-0.64], P=0.671 · SPI: AUC 0.46 [0.31-0.61], P=0.621 · PPI: AUC 0.52 [0.36-0.68], P=0.770 · NOL: AUC 0.66 [0.51-0.81], P=0.038

Lidocaine Intraoperative Infusion Pharmacokinetics during Partial Hepatectomy for Living Liver Donation

2026-10-28T03:16:58.759Z

Research article · Anesthesiology, 2022. Lidocaine elimination clearance: Typical lidocaine elimination clearance, baseline (± SE of the estimate) 0.55 ± 0.12 l/min