CurrentAnesthesia — Pediatric anesthesia & critical care

Effects of an Immersive Virtual Reality Intervention on Pain and Anxiety Among Pediatric Patients Undergoing Venipuncture: A Randomized Clinical Trial

2026-10-28T04:44:26.953Z

Randomized controlled trial · JAMA Netw Open, 2023. Child-reported pain, immediately after the intervention — IVR vs Control: β -0.78 (95% CI -1.21 to -0.35); P < .001

Impact of Tele-Emergency Consultations on Pediatric Interfacility Transfers: A Cluster-Randomized Crossover Trial

2026-10-28T04:44:26.953Z

Randomized controlled trial · JAMA Netw Open, 2023. Risk of transfer — Telemedicine vs Telephone: RR 0.93 (95% CI 0.88-0.99); adjusted for age, severity of illness, hospital study period

Trends in In-Hospital Cardiac Arrest and Mortality Among Children With Cardiac Disease in the Intensive Care Unit: A Systematic Review and Meta-analysis

2026-10-28T04:44:26.953Z

Meta-analysis · JAMA Netw Open, 2023. Incidence of IHCA and in-hospital mortality: Incidence of IHCA (pooled) 5% (95% CI, 4%-6%)

Effect of Early High-Flow Nasal Oxygen vs Standard Oxygen Therapy on Length of Hospital Stay in Hospitalized Children With Acute Hypoxemic Respiratory Failure: The PARIS-2 Randomized Clinical Trial

2026-10-28T04:43:30.217Z

Randomized controlled trial · JAMA, 2023. Length of hospital stay: High-flow oxygen median 1.77 (IQR 1.03-2.80) days · Standard oxygen median 1.50 (IQR 0.85-2.44) days

A 30-Minute Spontaneous Breathing Trial Misses Many Children Who Go On to Fail a 120-Minute Spontaneous Breathing Trial

2026-10-28T04:40:50.491Z

Secondary analysis · Chest, 2022. SBT outcome and 30-min prediction: SBTs successful 42%

Descriptive statistics and risk factor analysis of children with community-acquired septic shock

2026-10-28T04:36:50.728Z

Cohort study · J Intensive Care, 2023. In-hospital mortality: Children 244 (32.1%)

The outcome of acute kidney injury substages based on urinary cystatin C in critically ill children

2026-10-28T04:30:32.433Z

Cohort study · Ann Intensive Care, 2023. 30-day PICU mortality, 30 days — Sub-AKI vs Non-AKI: aHR 2.42; significant after adjustment for confounders

Cerebrovascular Pressure Reactivity Has a Strong and Independent Association With Outcome in Children With Severe Traumatic Brain Injury*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. PRx and mortality: PRx consistently higher in patients with poor outcome; strong, independent association with mortality (ROC AUC) 0.91

Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2022. Survival to hospital discharge — Mean DBP greater than 25 mm Hg for infants and greater than 30 mm Hg for older children vs DBP below threshold: aRR for survival to discharge 1.32 (CI 1.01-1.74); p = 0.03; multivariable Poisson regression

Fluid Overload Precedes and Masks Cryptic Kidney Injury in Pediatric Acute Respiratory Distress Syndrome

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. Conventionally defined AKI incidence and outcomes, days 1-7 of ARDS: Early AKI 10% · Late AKI 3% · Persistent AKI 13%

Impact of the Magnitude and Timing of Fluid Overload on Outcomes in Critically Ill Children: A Report From the Multicenter International Assessment of Worldwide Acute Kidney Injury, Renal Angina, and Epidemiology (AWARE) Study

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. Frequency of FO thresholds: FO ≥ 5%Day1 1753 (38.1%) · FO ≥ 10%Day1 537 (11.7%) · FO ≥ 5%Day2 1,539 (53.3%) · FO ≥ 10%Day2 724 (25.1%)

Implementation of Video Laryngoscope-Assisted Coaching Reduces Adverse Tracheal Intubation-Associated Events in the PICU*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. TIAEs: VL 336 (9.4%) · SL 215 (14.5%)

The Association Between Central Line-Associated Bloodstream Infection and Central Line Access*

2026-10-28T04:21:38.918Z

Cohort study · Crit Care Med, 2023. CLABSI in the next 3 days per daily CL access — Per-day CL accesses: aOR 1.007 (95% CI 1.003-1.012); p = 0.002; independently associated

Effect of apneic oxygenation with intubation to reduce severe desaturation and adverse tracheal intubation-associated events in critically ill children

2026-10-28T04:14:48.087Z

Research article · Crit Care, 2023. Adverse TIAEs: AO 10.5% · without AO 13.5%

Serum-integrated omics reveal the host response landscape for severe pediatric community-acquired pneumonia

2026-10-28T04:14:48.087Z

Mechanistic study · Crit Care, 2023. Serum proteomic and metabolic signature: Proteomic and metabolic signature markedly different between S-CAPs, NS-CAPs and CONs

The rapid detection of respiratory pathogens in critically ill children

2026-10-28T04:14:48.087Z

Diagnostic or prognostic study · Crit Care, 2023. Sensitivity and specificity of TAC, and time to result: TAC: sensitivity 89.5% (confidence interval (CI95) 66.9-98.7); specificity 97.9% (CI95 97.2-98.5) · TAC median 25.8 (IQR 9.1-29.8) h · Culture median 110.4 (IQR 85.2-141.6) h; positive result 110.4 h · Culture median 69.4 (IQR 52.8-78.6) h; negative result 69.4 h

Variation in electroencephalography and neuroimaging for children receiving extracorporeal membrane oxygenation

2026-10-28T04:14:48.087Z

Cohort study · Crit Care, 2023. Frequency of EEG, cranial ultrasound, brain CT, MRI and transcranial Doppler during ECMO hospitalizations; hospital variation: Cranial ultrasound in children <1 year 5389/5582

Clinical practice guidelines: management of severe bronchiolitis in infants under 12 months old admitted to a pediatric critical care unit

2026-10-28T04:13:06.971Z

Guideline or statement · Intensive Care Med, 2023.

Intraoperative hypothermia in the neonate population: risk factors, outcomes, and typical patterns

2026-10-28T04:08:44.882Z

Cohort study · J Clin Monit Comput, 2022. Incidence of intraoperative hypothermia (< 36 °C): Incidence of intraoperative hypothermia 81.05%

Assessing the utility of ultrasound‐guided vascular access placement with longer catheters in critically ill pediatric patients

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2023. Intravenous failure: Traditional median 108 h · Ultrasound-guided median 219 h

Bleeding and ketorolac use in pediatric circumcision

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2023. Postoperative bleeding requiring intervention, first 24 h: Ketorolac 4 (0.93%) · Non-ketorolac 1 (0.32%)

Children's perioperative multidimensional anxiety scale: Turkish cross‐cultural adaptation

2026-10-28T04:04:03.147Z

Diagnostic or prognostic study · Paediatr Anaesth, 2023. Validity and reliability of Turkish CPMAS: Internal consistency (Cronbach's alpha) 0.858, 0.916, 0.864

Comparative efficacy of finger versus forehead Plethysmographic Variability Index monitoring in pediatric surgical patients

2026-10-28T04:04:03.147Z

Diagnostic or prognostic study · Paediatr Anaesth, 2022. Prediction of fluid responsiveness (≥ 15% increase in CO after passive leg raise), prior to passive leg raise maneuver: Finger AUC 0.699; p p = .011 · Forehead AUC 0.847; p p < .001 · Finger: cut-off ≤14%; sensitivity 92.9%; specificity 45.4% · Forehead: cut-off ≤14%; sensitivity 96.4%; specificity 72.7%

Comparison of intravenous and inhalation anesthesia on postoperative behavior changes in children undergoing ambulatory endoscopic procedures: A randomized clinical trial

2026-10-28T04:04:03.147Z

Randomized controlled trial · Paediatr Anaesth, 2022. Postoperative negative behaviors, Days 1, 7, and 14: Median number of negative behaviors similar between the groups

Development and validation of a prediction model for preoperative anxiety in children aged 2–12 years old

2026-10-28T04:04:03.147Z

Diagnostic or prognostic study · Paediatr Anaesth, 2022. Model discrimination: Derivation: AUC 0.961 (95% CI = 0.943-0.979) · Validation: AUC 0.896 (95% CI = 0.842-0.950)

Effects of virtual tour on perioperative pediatric anxiety

2026-10-28T04:04:03.147Z

Randomized controlled trial · Paediatr Anaesth, 2023. Yale Preoperative Anxiety Scale: VT+ mean 27.26; median 23.4 (CI 95% 23.4-23.4) · VT- mean 32.57; median 23.4 (CI 95% 23.4-33.4)

Factors associated with immediate and early extubation in pediatric living‐donor liver transplant recipients

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2022. Factors associated with early extubation (univariate and multivariate analyses): Early extubation 31 (39%); immediately extubated in operating room 19 (24%); extubated early, within 24 h 12 (15%)

Gastric emptying times of obese and non‐obese school‐aged children after preoperative clear fluid intake: A prospective observational study

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2023. Gastric emptying time: Non-obese median 35 (IQR [range] 30.0-45.0 (20-60)) minutes · Obese median 35 (IQR [range] 30.0-40.0 (25-60)) minutes

Impact of intravenous dexamethasone on the initiation and recovery of atracurium in children: A double‐blinded randomized controlled trial

2026-10-28T04:04:03.147Z

Randomized controlled trial · Paediatr Anaesth, 2022. Onset time and recovery index of atracurium: Dexamethasone 1.96 (± 0.39); recovery index 8.04 ± 2.14 · Saline 2.01 (± 0.51); recovery index 8.9 ± 3.4

Justification of empiric methodology to determine dexmedetomidine dose for the TREX study

2026-10-28T04:04:03.147Z

Secondary analysis · Paediatr Anaesth, 2022. Dexmedetomidine plasma concentrations: Observed plasma concentrations consistent with those predicted by a "universal" model using pooled data from neonates to adults

Modeling iatrogenic intraoperative hyperthermia from external warming in children: A pooled analysis from two prospective observational studies

2026-10-28T04:04:03.147Z

Meta-analysis · Paediatr Anaesth, 2022. Core temperature increase over time: Mean temperature increase after 1 h 0.43°C

Needleless inhaled anesthesia with sevoflurane: Advantages of a simplified approach for children with spinal muscular atrophy undergoing intrathecal administration of nusinersen

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2023. Predefined sentinel adverse events related to anesthesia (prolonged desaturation): Cases of prolonged desaturation (sentinel adverse events) during anesthesia, of 250 lumbar punctures 2

Point‐of‐care ultrasonography to predict fluid responsiveness in children: A systematic review and meta‐analysis

2026-10-28T04:04:03.147Z

Meta-analysis · Paediatr Anaesth, 2022. Pooled accuracy for fluid responsiveness: ∆Vpeak: Sensitivity 0.84 (95% CI, 0.76-0.90); Specificity 0.82 (95% CI, 0.75-0.87); AUSROC 0.89 (95% CI, 0.86-0.92) · ∆IVC: Sensitivity 0.79 (95% CI, 0.62-0.90); Specificity 0.70 (95% CI, 0.51-0.84); AUSROC 0.81 (95% CI, 0.78-0.85)

Postanesthesia complications in pediatric patients with previous SARS‐CoV‐2 infection: A cohort study

2026-10-28T04:04:03.147Z

Case-control study · Paediatr Anaesth, 2022. All postanesthesia complications within 30 days — Positive test 0-7 days prior to anesthesia: risk difference 19.9 (95% CI 4.7, 35.1); p = .001

Postoperative recovery in children: Turkish cross‐cultural adaptation

2026-10-28T04:04:03.147Z

Diagnostic or prognostic study · Paediatr Anaesth, 2023. Validity and reliability of Turkish PRiC: Three-factor structure; variance explained 68%

Preoperative clear fluid fasting and endoscopy‐measured gastric fluid volume in children

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2023. Correlation between clear fluid fasting time and residual gastric fluid volume per kg body weight (endoscopic aspiration): Correlation of clear fluid fasting time with residual gastric volume per kg: r = -.103, p = .1 (not significant)

Regional oxygen saturation measured by two different oximetry monitors in infants and children undergoing living donor liver transplantation with bilirubin measurements: A prospective observational study

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2022. Cerebral and somatic rSO2 (linear mixed effects model): Cerebral rSO2 differed by time p = .031

Relationship between decrement time and recovery time in pediatric total intravenous anesthesia with propofol and remifentanil

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2023. Decrement time vs recovery time: Median decrement time (IQR 8.3-21) 11.8 min

Risk assessment of postoperative pneumonia in children with neurologic disorders and obesity

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2022. Association between neurologic disorders and postoperative pneumonia, by BMI subgroup: Overweight: HR 11.88 · Healthy weight: HR 9.45 · Obese: HR 4.40

Standardized Anesthesia InductioN Tool (SAINT) – The development and international adoption of an integrated electronic tool for documenting the induction of anesthesia in children

2026-10-28T04:04:03.147Z

Research article · Paediatr Anaesth, 2023. Development and adoption of SAINT: Electronic tool SAINT developed, incorporating validated scales for key induction stages (separation from caregivers, mask acceptance, induction behaviour, parental presence, adjuncts and their effectiveness)

Trends in pediatric non‐operating room anesthesia: Data from the National Anesthesia Clinical Outcomes Registry

2026-10-28T04:04:03.147Z

Cohort study · Paediatr Anaesth, 2023. Proportion of pediatric anesthetics in non-operating room settings: Pediatric anesthetics occurring in non-operating room settings 22.7%

An Assessment of the Practice of Neuromuscular Blockade and the Association Between Its Prophylactic Use and Outcomes Among Postoperative Pediatric Cardiac Patients

2026-10-28T03:56:35.329Z

Cohort study · J Cardiothorac Vasc Anesth, 2023. Composite of MAEs: death from any cause, circulatory collapse needing CPR, or requirement for ECMO, within 7 days after surgery: pNMBA 5.3% · non-pNMBA 0.6%

The Analgesic Effects of the Addition of Intravenous Ibuprofen to a Multimodal Analgesia Regimen for Pain Management After Pediatric Cardiac Surgery: A Randomized Controlled Study

2026-10-28T03:56:35.329Z

Randomized controlled trial · J Cardiothorac Vasc Anesth, 2022. Total fentanyl consumption, first 24 h after extubation, 24 hours: Ibuprofen mean 3.5 ± 1.3 μg/kg · Control mean 5.1 ± 1.4 μg/kg

Current Anesthesia Practices of Pediatric Cardiac Surgeries in Tertiary Maternity and Children's Hospitals in China: A National Survey

2026-10-28T03:56:35.329Z

Cross-sectional study · J Cardiothorac Vasc Anesth, 2023. Pediatric cardiac anesthesia practices: caseloads, geographic distribution, anesthetic regimens, monitoring, postoperative analgesia, anesthesiologist qualifications: Hospitals agreed to participate (of 130 confirmed) 108

Effects of Dexmedetomidine on Brain and Inflammatory Outcomes In Pediatric Cardiac Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2026-10-28T03:56:35.329Z

Meta-analysis · J Cardiothorac Vasc Anesth, 2023. Brain markers (NSE, S-100β) and inflammatory markers (interleukin-6, TNF-α, NF-κB), during and after cardiac surgery — Dexmedetomidine vs Normal saline: SMD (NSE) -0.54 (95% CI -0.96 to -0.12); within 24 hours; 5 treatment groups in 3 RCTs, 260 children

Levosimendan or Milrinone for Ventricular Septal Defect Repair With Pulmonary Arterial Hypertension

2026-10-28T03:56:35.329Z

Randomized controlled trial · J Cardiothorac Vasc Anesth, 2023. Low-cardiac-output syndrome / myocardial performance index: No difference in the myocardial performance index of the left or right ventricle

The Anti-Inflammatory and Antioxidant Effects of Propofol and Sevoflurane in Children With Cyanotic Congenital Heart Disease

2026-10-28T03:56:35.329Z

Randomized controlled trial · J Cardiothorac Vasc Anesth, 2022. Anti-inflammatory and antioxidant effects (systemic inflammatory response syndrome (SIRS), IL-6, TNF-α, total antioxidant status (TAS), TOS) — group S vs group P; p = 0.020; SIRS more common in group S, end of surgery

Median effective dose of 0.2% ropivacaine for ultrasound-guided median nerve block in young children

2026-10-28T03:54:35.559Z

Research article · Anaesth Crit Care Pain Med, 2022. ED50: 1- to 3-year-olds ED50 0.9 (95% CI 0.44-1.36) mL · 3- to 6-year-olds ED50 1.4 (95% CI 1.14-1.66) mL

Nociception level response to calibrated stimulations in children: First assessment of the nociception level index in pediatric anesthesia

2026-10-28T03:54:35.559Z

Mechanistic study · Anaesth Crit Care Pain Med, 2023. NOL response: NOL increased after the stimulations at each intensity p < 0.05

Non-invasive measurement of digital plethysmographic variability index to predict fluid responsiveness in mechanically ventilated children: A systematic review and meta-analysis of diagnostic test accuracy studies

2026-10-28T03:54:35.559Z

Meta-analysis · Anaesth Crit Care Pain Med, 2023. Prediction of fluid responsiveness: PVI: AUC (summary ROC) 0.82; Pooled sensitivity 72.4% [95% CI: 65.3-78.7]; Pooled specificity 65.9% [58.5-72.8]; Diagnostic OR 9.26 [5.31-16.16]