Perioperative medicine & outcomes

A new risk calculation model for complications of hepatectomy in adults over 75

Perioper Med (Lond)Published Risk prediction model development study

Authors' conclusion

RASHA can be used to effectively predict the postoperative complications of hepatectomy through perioperative variables in adults older than 75 years.

Study context

Population
Adults older than 75 years undergoing hepatectomy
Participants
326 participants
Comparison
Risk Assessment System of Hepatectomy in Adults (RASHA) scale vs RASHA formula
Outcome
Postoperative complications (Clavien-Dindo classification ≥ II)
Methodological detailslogistic regression model
  • Logistic regression model

Main finding

As reported in the abstract

Prediction of postoperative complications
GroupAUCCut-off
RASHA scale0.91612.5
RASHA formula0.8010.2106

AUC

RASHA scale0.916
RASHA formula0.801

Cut-off

RASHA scale12.5
RASHA formula0.2106

Further findings

OutcomeORP value
Independent risk factors for postoperative complications (multivariate analysis)Comorbidity ≥ 5 kinds of disease vs < 5 kinds of disease5.552P < 0.001
Independent risk factors for postoperative complications (multivariate analysis)Fatigue yes vs no4.630P = 0.009
Independent risk factors for postoperative complications (multivariate analysis)Child-Pugh B vs A4.211P = 0.004
Independent risk factors for postoperative complications (multivariate analysis)Liver segments removed ≥ 3 vs ≤ 24.101P = 0.001
Independent risk factors for postoperative complications (multivariate analysis)Adjacent organ resection yes vs no1.523P = 0.010

Original publication

A new risk calculation model for complications of hepatectomy in adults over 75. Perioper Med (Lond). Published 26 February 2024. doi:10.1186/s13741-024-00366-y

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