Perioperative medicine & outcomes
A protocol for a pilot study to assess the feasibility of a randomised clinical trial of perioperative intravenous lidocaine on colorectal cancer outcome after surgery (FLICOR trial)
Study context
- Population
- Patients undergoing minimally invasive (laparoscopy or robotic) colorectal cancer surgery
- Planned comparison
- Perioperative IV lidocaine vs placebo
- Primary endpoint
- Feasibility of conducting a clinical trial of perioperative IV lidocaine for postoperative colorectal cancer outcomes
Methodological detailsdouble-blinded, placebo-controlled, two NHS Trusts, Patient and clinician feedback on study process, Recruitment planned at two NHS Trusts over 6 months with 12-month follow-up, Exploratory blood samples before and after surgery on days 0, 1 and 3
- Double-blinded
- Placebo-controlled
- Two NHS Trusts
- Patient and clinician feedback on study process
- Recruitment planned at two NHS Trusts over 6 months with 12-month follow-up
- Exploratory blood samples before and after surgery on days 0, 1 and 3
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
A protocol for a pilot study to assess the feasibility of a randomised clinical trial of perioperative intravenous lidocaine on colorectal cancer outcome after surgery (FLICOR trial). BJA Open. Published June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →