ICU sedation, delirium & recovery
Acute amiodarone‐induced pulmonary toxicity in adult intensive care unit (ICU) patients with new‐onset atrial fibrillation—A systematic review
Authors' conclusion
Acute APT in adult ICU patients treated with amiodarone for NOAF is poorly described and is based on a total of 16 reported cases.
Study context
- Population
- Adult ICU patients with new-onset atrial fibrillation or flutter (NOAF) treated with amiodarone9 case reports · 1 case series
- Participants
- 16 patients
- Outcome
- Acute amiodarone-induced pulmonary toxicity (APT)
Pooled result
As reported in the abstract
Acute APT cases
Critically ill adults diagnosed with acute APT
16
Time to APT diagnosis after amiodarone initiation, mean (range 2-20 days)
9 days
Total amiodarone dose, mean (range 1100-13,500 mg)
4553 mg
Study quality: CASE criteria fulfilled of 13, mean (range 8-12)
10
Further pooled results
| Outcome | Values |
|---|---|
| ICU death during amiodarone treatment (case reports)No long-term follow-up of survivors | Amiodarone 3 events |
- ICU death during amiodarone treatment (case reports): 3 of 9 patients in the case reports
Original publication
Acute amiodarone‐induced pulmonary toxicity in adult ICU patients with new‐onset atrial fibrillation—A systematic review. Acta Anaesthesiol Scand. Published 17 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →