Obstetric anaesthesia

Adherence to an intraoperative and post-cesarean analgesia protocol: a before-and-after implementation study in a large academic center (2024–2025)

Int J Obstet AnesthPublished Prospective before-and-after cohort study

Authors' conclusion

After implementation of protocols intended to improve post-cesarean analgesia, quasi-universal adherence to the intraoperative multimodal analgesia protocol was achieved within the first three months and was associated with significantly improved pain scores in the post-anesthesia care unit.

Study context

Population
Women undergoing term cesarean delivery, May 2024 to July 2025
Participants
202 women
Exposure
Pre-implementation vs Post-implementation
  • Pre-implementationn = 101reference
  • Post-implementationn = 101
Outcome
Adherence to the intraoperative anaesthesia protocol and the postoperative nursing protocol
Methodological detailssingle-centre, implementation study, Adherence assessed by investigator-led audits of anaesthetic and electronic medical records
  • Single-centre
  • Implementation study
  • Adherence assessed by investigator-led audits of anaesthetic and electronic medical records

Main finding

As reported in the abstract

Intraoperative adherence by 10 months

96%

Postoperative adherence POD 1

71.3%

Postoperative adherence POD 2

13.9%

Postoperative adherence POD 3

3%

Observational data: associations, not effects.

Secondary outcomes

Pain (VAS >3) in PACU

Incidence of pain (VAS >3) in PACU decreased from 33.6% to 4%

Postoperative pain (VAS >3), POD 1-3

Pain (VAS >3) POD 1
52.5%
Pain (VAS >3) POD 2
60.4%
Pain (VAS >3) POD 3
24.8%
  • Persistently high rates

Original publication

Adherence to an intraoperative and post-cesarean analgesia protocol: a before-and-after implementation study in a large academic center (2024–2025). Int J Obstet Anesth. Published 16 June 2026. doi:10.1016/j.ijoa.2026.105221

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