Cardiac arrest & resuscitation

Advanced life support interventions during intra‐operative cardiac arrest among adults as reported to the 7th National Audit Project of the Royal College of Anaesthetists

AnaesthesiaPublished Analysis of a national audit registry

Authors' conclusion

The specific characteristics of intra-operative cardiac arrest imply that its optimal treatment requires modifications to standard advanced life support guidelines.

Study context

Population
Adults (aged > 18 years) with intra-operative cardiac arrest during anaesthesia (induction to emergence) for non-obstetric proceduresof 881 registry patients
Participants
548 adults
Outcome
Incidence and outcome of intra-operative cardiac arrest; ALS interventions used by anaesthetists
Methodological details7th National Audit Project of the Royal College of Anaesthetists, baseline survey
  • 7th National Audit Project of the Royal College of Anaesthetists
  • Baseline survey

Main finding

As reported in the abstract

Outcome after intra-operative cardiac arrest

Sustained ROSC

425

78%

Alive at time of reporting

338

62%

Observational data: associations, not effects.

Further findings

ALS interventions

Adrenaline 1 mg bolus in patients with pulseless electrical activity or bradycardia (n = 365)
237 (65%)
Precordial thump
14 (3%)
Precordial thump: initial rhythm shockable
1
Calcium (gluconate or chloride)
51 (9%)
8.4% sodium bicarbonate
25 (5%)
Thrombolytic drug
5 (1%)
ECPR
9 (2%)
ECPR during cardiac procedures
8
  • Specific indications for calcium and bicarbonate in less than half of patients
  • Precordial thump associated with ROSC at next rhythm check in almost three-quarters

Baseline survey: threshold to start chest compressions

Anaesthetists who would start compressions at non-invasive systolic pressure < 40-50 mmHg
> 50%

Original publication

Advanced life support interventions during intra‐operative cardiac arrest among adults as reported to the 7th National Audit Project of the Royal College of Anaesthetists. Anaesthesia. Published 10 May 2024. doi:10.1111/anae.16310

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