Safety, quality & education

Adverse events leading to intensive care unit admission in a low-and-middle-income-country: A prospective cohort study and a systematic review

J Crit CarePublished Prospective cohort study and systematic review with meta-analysis

Authors' conclusion

In this prospective cohort, adverse events were a relevant reason for ICU admission. This result is consistent with data retrieved from non-LMIC as shown in our meta-analysis.

Study context

Population
Adults admitted to two general ICUs of a tertiary public academic hospital in a LMIC
Outcome
Rate of adverse event-related ICU admissions and their preventability
Methodological detailstwo general ICUs, tertiary public academic hospital, one-year period
  • Two general ICUs
  • Tertiary public academic hospital
  • One-year period

Pooled result

As reported in the abstract

AE-related ICU admissions (cohort)
ICU admissions related to an adverse events (AE)
12.1%
Caused by an AE
9.8%
Related but not directly caused by an AE
2.3%
Preventability rate of AE-related admissions
70.9%
Potentially preventable AE-related admissions, of all ICU admissions
8.6%

Further pooled results

Mortality of AE-related ICU admissions

Not associated with a higher risk of death

Meta-analysis: proportion of ICU admissions due to AE

Proportion of ICU admissions due to AE
11% (95% CI 6%-16%)
Preventability rate
54% (95% CI 42%-66%)

Original publication

Adverse events leading to intensive care unit admission in a low-and-middle-income-country: A prospective cohort study and a systematic review. J Crit Care. Published 26 December 2023. doi:10.1016/j.jcrc.2023.154510

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