Pediatric anesthesia & critical care

Airway Management in Children Undergoing Cleft Lip or Cleft Palate Surgery: An 8‐Year Retrospective Analysis of 274 Cases

Paediatr AnaesthPublished Retrospective cohort study

Authors' conclusion

Airway management in children undergoing cleft lip or palate surgery presents unique challenges, with an increased incidence of difficult and failed direct laryngoscopy and a significantly higher rate of complications in patients with a syndromic disorder.

Study context

Population
Children younger than 2 years undergoing cleft lip or palate surgery at a German university hospital, 2016–2023
Participants
274 cases
Exposure
Syndromic vs non-syndromic cleft patients
Outcome
Perioperative airway management and complications
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Difficult laryngoscopy

16 cases

6%

Failed direct laryngoscopy, followed by successful video-laryngoscopic intubation

five cases (1.9%)

Primary hybrid technique for expected difficult airway (proven syndromic disorder)

eight cases (2.9%)

Observational data: associations, not effects.

Further findings

Difficult laryngoscopy (subgroup: syndrome association)

Failed direct laryngoscopy (subgroup: syndrome association)

Safety

Airway complications

Significantly more common in patients with a syndromic disorder: 40.7% vs. 23.5%
P = 0.049
  • φ = 0.12

Original publication

Airway Management in Children Undergoing Cleft Lip or Cleft Palate Surgery: An 8‐Year Retrospective Analysis of 274 Cases. Paediatr Anaesth. Published 16 August 2025. doi:10.1111/pan.70038

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