Pain medicine

An updated systematic review and consensus definitions for standardised endpoints in perioperative medicine: patient comfort and pain relief

Br J AnaesthPublished Systematic review and Delphi consensus

Methodological detailsmulti-round Delphi, focus groups, workshops, patient and public involvement, qualitative analyses, Response rates 100% in each Delphi round, Consensus: median item score ≥7 and ≥70% of responses scoring ≥7 on a 9-point Likert scale
  • Multi-round Delphi
  • Focus groups
  • Workshops
  • Patient and public involvement
  • Qualitative analyses
  • Response rates 100% in each Delphi round
  • Consensus: median item score ≥7 and ≥70% of responses scoring ≥7 on a 9-point Likert scale

Recommendations

As issued by the authors

  1. Eight endpoints: supplementary analgesic use, subjective analgesic effectiveness, pain intensity (at rest, during movement, at 12, 24 and 72 h), postoperative nausea and vomiting (PONV) (0-6 h, 6-24 h, overall), postdischarge nausea and vomiting (PDNV), severe PONV, quality of recovery (QoR-15), time to mobilisation

  2. All endpoints assessed as valid, reliable, feasible and patient-centred

  3. At least some of these endpoints should be included as outcome measures in trials assessing patient comfort and pain after surgery

Original publication

An updated systematic review and consensus definitions for standardised endpoints in perioperative medicine: patient comfort and pain relief. Br J Anaesth. Published 24 March 2025. doi:10.1016/j.bja.2025.02.025

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