An updated systematic review and consensus definitions for standardised endpoints in perioperative medicine: patient comfort and pain relief
Methodological detailsmulti-round Delphi, focus groups, workshops, patient and public involvement, qualitative analyses, Response rates 100% in each Delphi round, Consensus: median item score ≥7 and ≥70% of responses scoring ≥7 on a 9-point Likert scale
- Multi-round Delphi
- Focus groups
- Workshops
- Patient and public involvement
- Qualitative analyses
- Response rates 100% in each Delphi round
- Consensus: median item score ≥7 and ≥70% of responses scoring ≥7 on a 9-point Likert scale
Recommendations
As issued by the authors
Eight endpoints: supplementary analgesic use, subjective analgesic effectiveness, pain intensity (at rest, during movement, at 12, 24 and 72 h), postoperative nausea and vomiting (PONV) (0-6 h, 6-24 h, overall), postdischarge nausea and vomiting (PDNV), severe PONV, quality of recovery (QoR-15), time to mobilisation
All endpoints assessed as valid, reliable, feasible and patient-centred
At least some of these endpoints should be included as outcome measures in trials assessing patient comfort and pain after surgery
Original publication
An updated systematic review and consensus definitions for standardised endpoints in perioperative medicine: patient comfort and pain relief. Br J Anaesth. Published 24 March 2025. doi:10. 1016/ j. bja. 2025. 02. 025
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