Cardiac arrest & resuscitation
Analysis of factors associated with favorable neurological outcomes in patients with initial pulseless electrical activity (PEA) who underwent extracorporeal cardiopulmonary resuscitation (ECPR) - A secondary analysis of the SAVE-J II study
Authors' conclusion
This study provides an overview of patients with PEA who underwent ECPR. Since several factors are associated with favorable neurological outcomes, patients with PEA may be candidates for ECPR if these factors are met.
Study context
- Population
- Patients with initial pulseless electrical activity (PEA) who underwent ECPR, 36 institutions in Japan36 institutions
- Primary endpoint
- Favorable neurological outcomes
- Follow-up
- Hospital discharge
Methodological detailsretrospective cohort study, multicentre registry, multivariate analysis, classification and regression tree analysis
- Retrospective cohort study
- Multicentre registry
- Multivariate analysis
- Classification and regression tree analysis
Primary result
As reported in the abstract
Favorable neurological outcomes and survival
Favorable neurological outcomes, overall
8.2 %
Survival rate at hospital discharge
16.9 %
Further findings
Favorable neurological outcomes by cause of cardiac arrest (subgroup)
%
- Acute coronary syndrome
- 9.7
- PE
- 19.3
- No patients with acute aortic disease or primary cerebral disease survived
Favorable neurological outcomes with strict PEA criteria (classification and regression tree analysis)
- Favorable neurological outcomes
- 32.7 %
Original publication
Analysis of factors associated with favorable neurological outcomes in patients with initial PEA who underwent ECPR - A secondary analysis of the SAVE-J II study. J Crit Care. Published 25 September 2024. doi:10.
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