Anesthetic management of cesarean delivery in patients with acute fatty liver of pregnancy: a retrospective single-center study (2018–2026)
Authors' conclusion
Single-shot spinal anesthesia was feasible in patients with acute fatty liver of pregnancy, whereas general anesthesia was used in patients with more severe disease or emergency obstetric indications.
Study context
- Population
- Patients with acute fatty liver of pregnancy (Swansea criteria) undergoing cesarean delivery, single hospital, January 2018–June 202620 identified, 5 excluded
- Participants
- 15 patients
- Exposure
- Single-shot spinal anesthesia vs Continuous spinal anesthesia vs GA
- Single-shot spinal anesthesian = 11
- Continuous spinal anesthesian = 1
- GAn = 3
- Outcome
- Anesthetic technique and maternal outcomes
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Death in GA group 16 h after delivery
1
Postpartum encephalopathy and transient diabetes insipidus, single-shot spinal group
1
Persistent hyperbilirubinemia, single-shot spinal group
1
Observational data: associations, not effects.
Original publication
Anesthetic management of cesarean delivery in patients with acute fatty liver of pregnancy: a retrospective single-center study (2018–2026). Int J Obstet Anesth. Published 10 September 2026. doi:10.
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