Antepartum obstructive sleep apnea screening and its association with postpartum respiratory depression: a retrospective cohort study (2020–2025)
Main finding · Postpartum oxygen desaturation and bradypneaResult — go to the resultAdjusted odds ratio 1.86 95% CI 1.21–2.88Authors' conclusion
Positive antepartum STOP screening was associated with postpartum desaturation but not bradypnea.
Study context
- Population
- Parturients undergoing routine antepartum OSA STOP screening, delivery encounters with ≥1 STOP response, July 2020 to June 2025
- Participants
- 19,250 delivery encounters
- Exposure
- Positive vs negative antepartum OSA STOP screening
- Positive STOP screeningn = 608
- Outcome
- Postpartum respiratory outcomes: bradypnea, oxygen desaturation, naloxone administration
Methodological detailssingle-centre
- Single-centre
Main finding
Postpartum oxygen desaturation and bradypnea
Adjusted odds ratio
1.86
95% CI 1.21–2.88
P = 0.005
Positive STOP screening vs Negative STOP screening
aOR 1.86 (95% CI 1.21–2.88); P = 0.005
As reported in the abstract
Observational data: associations, not effects.
Further findings
Preeclampsia or hypertensive diagnosis
| OR (95% CI) | ||
|---|---|---|
| Preeclampsia or hypertensive diagnosisBradypnea | 1.64 (1.14–2.35) | |
| Preeclampsia or hypertensive diagnosisDesaturation | 2.88 (2.06–4.03) | |
| 0.20.5125Odds ratio (log scale) |
Self-reported OSA
| OR (95% CI) | ||
|---|---|---|
| Self-reported OSABradypnea | 2.01 (1.06–3.84) | |
| Self-reported OSADesaturation | 2.72 (1.46–5.08) | |
| 0.20.5125Odds ratio (log scale) |
- Self-reported OSA — Self-reported OSA
- 182 (1.0%)
Overall incidence of bradypnea and oxygen desaturation
- Bradypnea
- 2.8% (532/19,237)
- Oxygen desaturation
- 2.4% (356/14,723)
Individual STOP components
- Snoring, tiredness and observed apnea associated with desaturation but not bradypnea
Original publication
Antepartum obstructive sleep apnea screening and its association with postpartum respiratory depression: a retrospective cohort study (2020–2025). Int J Obstet Anesth. Published 28 September 2026. doi:10.
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