Pediatric anesthesia & critical care
Apnoeic oxygenation during paediatric tracheal intubation: a systematic review and meta-analysis
Pooled result · Intubation first-pass successResult — go to the resultRR for first-pass success 1.27 95% CI 1.03–1.57Authors' conclusion
This systematic review with meta-analysis confirms that apnoeic oxygenation during tracheal intubation of children significantly increases first-pass intubation success rate.
Study context
- Population
- Paediatric patients requiring tracheal intubation
- Participants
- 9,802 patients · 15 studies
- Comparison
- Apnoeic oxygenation vs no apnoeic oxygenation
- Outcome
- Intubation first-pass success
Methodological detailsGrading of Recommendations Assessment, Development, and Evaluation (GRADE) assessment, prospectively registered protocol
- GRADE assessment
- Prospectively registered protocol
Pooled result
As reported in the abstract
RR for first-pass success
1.27
95% CI 1.03–1.57
P = 0.04
Apnoeic oxygenation vs No apnoeic oxygenation
RR for first-pass success 1.27 (95% CI 1.03–1.57); P = 0.04
Further pooled results
| Outcome | Mean difference (%) (95% CI) | P value | |
|---|---|---|---|
| Oxygen saturation during intubationI2=63% | 3.6 (0.8–6.5%) | P = 0.02 | |
| −50510Difference, % (linear scale) |
Safety
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| HypoxaemiaI2=51% | 0.24 (0.17–0.33) | P < 0.01 | |
| 0.10.31310Relative risk (log scale) |
Original publication
Apnoeic oxygenation during paediatric tracheal intubation: a systematic review and meta-analysis. Br J Anaesth. Published 28 November 2023. doi:10.
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