Arterial partial pressure of oxygen as a marker of airway closure does not correlate with the efficacy of pre-oxygenation: A prospective cohort study
Authors' conclusion
After 3 min of pre-oxygenation, F E' O 2 , even in the elderly, indicated a high enough alveolar oxygen concentration to promote atelectasis after induction, therefore, it is still unclear why atelectasis formation diminishes after middle age.
Study context
- Population
- Adults aged 40 to 79 years presenting for elective noncardiac surgery, two regional hospitals in Sweden, 2018–2021
- Participants
- 120 adults
- Outcome
- Correlation between efficacy of pre-oxygenation (F E' O 2 after 3 min of pre-oxygenation) and PaO2 on room air
- Follow-up
- 3 min
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Correlation of F E' O 2 at 3 min with PaO2
No linear correlation between F E' O 2 at 3 min and PaO2 (Pearson's r)
−0.038
P = 0.684
Observational data: associations, not effects.
Further findings
Correlation of F E' O 2 at 3 min with age
- No linear correlation between F E' O 2 at 3 min and age (Pearson's r)
- −0.113, P = 0.223
F E' O 2 at 3 min, whole population
- Mean ± SD F E' O 2 at 3 min
- 0.87 ± 0.05
Original publication
Arterial partial pressure of oxygen as a marker of airway closure does not correlate with the efficacy of pre-oxygenation: A prospective cohort study. Eur J Anaesthesiol. Published 30 June 2023. doi:10. 1097/ eja. 0000000000001869
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