Perioperative medicine & outcomes

Artificial Intelligence–Assisted Point-of-Care Ultrasound for Evaluating Left Ventricular Ejection Fraction: A Systematic Review of Prospective Observational Studies

J Cardiothorac Vasc AnesthPublished Systematic review of prospective observational studies

Authors' conclusion

AI-assisted POCUS can approximate reference LVEF and reasonably classify reduced LVEF at the bedside, supporting its use as a screening and triage tool in settings in which comprehensive echocardiography is not immediately available.

Study context

Population
Patients in intensive care unit (ICU), ED, perioperative, ward, home or community settings12 studies
Comparison
Real-time artificial intelligence (AI)-assisted point-of-care ultrasound (POCUS) vs reference standard for left ventricular ejection fraction (LVEF)
Outcome
Agreement between AI-derived and reference LVEF
Methodological detailsnarrative synthesis, QUADAS-2 risk of bias appraisal, PubMed/MEDLINE, Embase and Cochrane searched from inception to June 11, 2025
  • Narrative synthesis
  • QUADAS-2 risk of bias appraisal
  • PubMed/MEDLINE, Embase and Cochrane searched from inception to June 11, 2025

Pooled result

As reported in the abstract

Correlation (r), range
0.56 to 0.92
Intraclass correlation coefficients, range
0.84 to 0.94
Bland-Altman limits of agreement, broad, often AI underestimating LVEF
≈−31.8% to +20.0%
Sensitivity at 50% threshold, range
70% to 93%
Specificity at 50% threshold, range
89% to 100%
AUC at 50% threshold, range
0.85 to 0.98
Weighted κ, range
0.49 to 0.83

Further pooled results

No study achieved a low risk of bias across all QUADAS-2 domains

Original publication

Artificial Intelligence–Assisted Point-of-Care Ultrasound for Evaluating Left Ventricular Ejection Fraction: A Systematic Review of Prospective Observational Studies. J Cardiothorac Vasc Anesth. Published 12 February 2026. doi:10.1053/j.jvca.2026.02.011

Composed by AI from the published abstract and checked against it. How Briefs are made →

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