Cardiac arrest & resuscitation
Assessing both early and late EEG patterns improves prediction of outcome after cardiac arrest
Authors' conclusion
Searching for both early EEG predictors (e.g. identical burst-suppression) and late EEG predictors (e.g. heterogenous burst-suppression > 24 h) significantly improved sensitivity of poor outcome prediction without false positive survivors in this cohort.
Study context
- Population
- Consecutive comatose resuscitated patients after cardiac arrest53 % poor outcome
- Participants
- 191 participants
- Comparison
- Early EEG predictors vs late EEG predictors vs both for outcome prediction
- Primary endpoint
- Prediction of poor outcome (modified Rankin Scale 4-6)
- Follow-up
- Six months
Methodological detailsobservational substudy, blinded EEG assessment
- Observational substudy
- Blinded EEG assessment
Primary result
As reported in the abstract
Poor outcome prediction
| Group | Maximal sensitivity (before 24 h) | Maximal sensitivity | Sensitivity (up to 36 h after cardiac arrest (CA)) | Specificity (all time-points) | Specificity (beyond 24 h) |
|---|---|---|---|---|---|
| Early EEG predictors | 30 %[CI 21-40] | — not stated in the abstract | — not stated in the abstract | 100 %[CI 96-100] | — not stated in the abstract |
| Late EEG predictors | — not stated in the abstract | 32 %[CI 21-43] | — not stated in the abstract | — not stated in the abstract | 100 %[CI 96-100] |
| Early and late EEG predictors | — not stated in the abstract | — not stated in the abstract | 49 %[CI 39-59] | — not stated in the abstract | — not stated in the abstract |
Maximal sensitivity (before 24 h)
Early EEG predictors30 %[CI 21-40]
Late EEG predictors— not stated in the abstract
Early and late EEG predictors— not stated in the abstract
Maximal sensitivity
Early EEG predictors— not stated in the abstract
Late EEG predictors32 %[CI 21-43]
Early and late EEG predictors— not stated in the abstract
Sensitivity (up to 36 h after cardiac arrest (CA))
Early EEG predictors— not stated in the abstract
Late EEG predictors— not stated in the abstract
Early and late EEG predictors49 %[CI 39-59]
Specificity (all time-points)
Early EEG predictors100 %[CI 96-100]
Late EEG predictors— not stated in the abstract
Early and late EEG predictors— not stated in the abstract
Specificity (beyond 24 h)
Early EEG predictors— not stated in the abstract
Late EEG predictors100 %[CI 96-100]
Early and late EEG predictors— not stated in the abstract
— not stated in the abstract
Further findings
Continuous background within 12 h predicting good outcome
- Sensitivity
- 61 %[CI 50-71]
- Specificity
- 87 %[CI 79-93]
Original publication
Assessing both early and late EEG patterns improves prediction of outcome after cardiac arrest. Resuscitation. Published 7 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →