Assessment of haemostasis in pregnant women: A retrospective evaluation of the diagnostic performance of the HEMSTOP standardised questionnaire
Authors' conclusion
In the conditions of our study, the HEMSTOP questionnaire enables the prediction of a primary haemostatic anomaly with a specificity and sensitivity comparable to routine haemostatic assessments.
Study context
- Population
- Full-term parturients with vaginal or caesarean delivery, Brugmann Hospital (tertiary university), January 2020–December 2021
- Participants
- 3,588 participants
- Outcome
- Sensitivity and specificity of HEMSTOP for identifying an abnormal primary haemostatic profile
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
As reported in the abstract
Abnormal standard coagulation test
| Group | Specificity | Sensitivity | NPV |
|---|---|---|---|
| HEMSTOP | 96% (95% CI, 0.95 to 0.97) | 39% (95% CI, 0.20 to 0.61) | 100% |
HEMSTOP
Specificity96% (95% CI, 0.95 to 0.97)
Sensitivity39% (95% CI, 0.20 to 0.61)
NPV100%
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Values |
|---|---|
| PPH (blood loss >1000 ml) | HEMSTOP specificity 96% (95% CI, 0.95 to 0.97) · sensitivity 8% (95% CI, 0.06 to 0.11) |
Original publication
Assessment of haemostasis in pregnant women: A retrospective evaluation of the diagnostic performance of the HEMSTOP standardised questionnaire. Eur J Anaesthesiol Intensive Care. Published 15 March 2024. doi:10. 1097/ ea9. 0000000000000050
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