Obstetric anaesthesia

Assessment of haemostasis in pregnant women: A retrospective evaluation of the diagnostic performance of the HEMSTOP standardised questionnaire

Eur J Anaesthesiol Intensive CarePublished Retrospective cohort study

Authors' conclusion

In the conditions of our study, the HEMSTOP questionnaire enables the prediction of a primary haemostatic anomaly with a specificity and sensitivity comparable to routine haemostatic assessments.

Study context

Population
Full-term parturients with vaginal or caesarean delivery, Brugmann Hospital (tertiary university), January 2020–December 2021
Participants
3,588 participants
Outcome
Sensitivity and specificity of HEMSTOP for identifying an abnormal primary haemostatic profile
Methodological detailssingle-centre, observational
  • Single-centre
  • Observational

Main finding

As reported in the abstract

Abnormal standard coagulation test
GroupSpecificitySensitivityNPV
HEMSTOP96% (95% CI, 0.95 to 0.97)39% (95% CI, 0.20 to 0.61)100%

HEMSTOP

Specificity96% (95% CI, 0.95 to 0.97)
Sensitivity39% (95% CI, 0.20 to 0.61)
NPV100%

Observational data: associations, not effects.

Secondary outcomes

OutcomeValues
PPH (blood loss >1000 ml)HEMSTOP specificity 96% (95% CI, 0.95 to 0.97) · sensitivity 8% (95% CI, 0.06 to 0.11)

Original publication

Assessment of haemostasis in pregnant women: A retrospective evaluation of the diagnostic performance of the HEMSTOP standardised questionnaire. Eur J Anaesthesiol Intensive Care. Published 15 March 2024. doi:10.1097/ea9.0000000000000050

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