ICU sedation, delirium & recovery
Association of anaesthesia‐directed sedation with unplanned discharge to a nursing home following non‐ambulatory interventional radiology and endoscopic procedures: a retrospective cohort study*
Authors' conclusion
Among patients undergoing a non-ambulatory interventional radiology procedure or a gastrointestinal endoscopy, anaesthetist-directed sedation is associated with a reduced risk of adverse discharge to a nursing home and a shorter duration of hospital stay.
Study context
- Population
- Adults previously living independently undergoing non-ambulatory interventional radiology or gastroenterology procedures under sedation, large healthcare network
- Participants
- 22,868 participants
- Exposure
- Anaesthetist-directed vs non-anaesthetist-directed sedation
- Anaesthetist-directed sedationn = 15,168
- Non-anaesthetist-directed sedationn = 7,700reference
- Outcome
- Postprocedural adverse discharge to a nursing home and postprocedural duration of hospital stay
Methodological detailsinstrumental variable analysis
- Instrumental variable analysis
Main finding
As reported in the abstract
Adverse discharge to a nursing home
Each group vs non-anaesthetist-directed sedationAdjusted relative risk (95% CI)P value
Anaesthetist-directed sedation
0.54(0.45–0.63)
P < 0.001Each group vs non-anaesthetist-directed sedationAdjusted risk difference (95% CI)P value
Anaesthetist-directed sedation
−4.6%(−5.8 to −3.4)
P < 0.001Observational data: associations, not effects.
Further findings
Postprocedural duration of hospital stay (co-primary)
adjusted model estimate 0.84 (0.79–0.89) · P < 0.001
| Outcome | Adjusted risk difference (95% CI) | P value | |
|---|---|---|---|
| Instrumental variable analysis: adverse discharge and hospital stayAdverse discharge to a nursing home | −4.3% (−8.4 to −0.1) | P = 0.043 | |
| −10−505Difference (linear scale) |
| Outcome | Difference (days) (95% CI) | P value | |
|---|---|---|---|
| Instrumental variable analysis: adverse discharge and hospital stayDuration of hospital stay | −1.41 (−1.43 to −1.41) | P < 0.001 | |
| −2−101Difference, days (linear scale) |
Proportion of missing BP measurements
P < 0.001
Proportion of missing BP measurements
- Mediated the effect of anaesthetist-directed sedation on adverse discharge
Original publication
Association of anaesthesia‐directed sedation with unplanned discharge to a nursing home following non‐ambulatory interventional radiology and endoscopic procedures: a retrospective cohort study*. Anaesthesia. Published 5 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →