The association between epidural labor analgesia and the fetal outcome and mode of delivery of the second twin: a nationwide register-based cohort study in Finland
Authors' conclusion
This study found epidural labor analgesia was associated with a lower rate of emergency cesarean delivery and neonatal mortality for the second twin.
Study context
- Population
- Twin pregnancies, second twin; National Medical Birth Register of Finland (2004–2018)twin pregnancies
- Participants
- 3,242 vs 2,780
- Exposure
- Epidural labor analgesia vs no epidural analgesia
- Epiduraln = 3,242
- Controln = 2,780reference
- Outcome
- Mode of delivery for the second twin (emergency and urgent cesarean section, assisted vaginal delivery)
Methodological detailsnationwide, register-based
- Nationwide
- Register-based
Main finding
As reported in the abstract
Cesarean delivery, second twin
Epidural vs ControlAdjusted odds ratio (95% CI)
All cesarean delivery
0.64(0.44–0.92)
Emergency cesarean delivery
0.52(0.33–0.79)
Observational data: associations, not effects.
Further findings
| Outcome | aOR (95% CI) |
|---|---|
| Neonatal mortality, second twin | 0.61 (0.73–0.90) |
Original publication
The association between epidural labor analgesia and the fetal outcome and mode of delivery of the second twin: a nationwide register-based cohort study in Finland. Int J Obstet Anesth. Published 11 August 2023. doi:10.
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