Pediatric anesthesia & critical care

Association Between Preoperative Iron Deficiency and Postoperative Outcomes in Children Undergoing Cardiac Surgery

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

Iron deficiency is common in children undergoing cardiac surgery and is associated with an increased risk of adverse outcomes.

Study context

Population
Children aged 0 to 18 years undergoing cardiac surgery with CPB, single academic quaternary children's hospital, 2019–2023
Participants
886 children
Exposure
Iron deficiency vs no iron deficiency
Outcome
Prevalence of iron deficiency and iron deficiency anemia and their association with adverse outcomes
Methodological detailssingle-centre, multivariable regression adjusted for surgical complexity and CPB time
  • Single-centre
  • Multivariable regression adjusted for surgical complexity and CPB time

Main finding

As reported in the abstract

Perioperative RBC transfusion volume

Iron deficiency vs Without iron deficiency: P < 0.001 · Iron deficiency anemia vs Normal iron and hemoglobin: P = 0.002

Observational data: associations, not effects.

Further findings

Postoperative AKI — Iron deficiency vs Without iron deficiency · persisted after adjustment

P = 0.002

OutcomeP value
Postoperative AKIIron deficiency anemia vs Normal iron and hemoglobin · persisted after adjustmentP = 0.006

Original publication

Association Between Preoperative Iron Deficiency and Postoperative Outcomes in Children Undergoing Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 15 May 2026. doi:10.1053/j.jvca.2026.05.030

Composed by AI from the published abstract and checked against it. How Briefs are made →

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