Pediatric anesthesia & critical care
Association Between Preoperative Iron Deficiency and Postoperative Outcomes in Children Undergoing Cardiac Surgery
Authors' conclusion
Iron deficiency is common in children undergoing cardiac surgery and is associated with an increased risk of adverse outcomes.
Study context
- Population
- Children aged 0 to 18 years undergoing cardiac surgery with CPB, single academic quaternary children's hospital, 2019–2023
- Participants
- 886 children
- Exposure
- Iron deficiency vs no iron deficiency
- Outcome
- Prevalence of iron deficiency and iron deficiency anemia and their association with adverse outcomes
Methodological detailssingle-centre, multivariable regression adjusted for surgical complexity and CPB time
- Single-centre
- Multivariable regression adjusted for surgical complexity and CPB time
Main finding
As reported in the abstract
Perioperative RBC transfusion volume
Iron deficiency vs Without iron deficiency: P < 0.001 · Iron deficiency anemia vs Normal iron and hemoglobin: P = 0.002
Observational data: associations, not effects.
Further findings
Postoperative AKI — Iron deficiency vs Without iron deficiency · persisted after adjustment
P = 0.002
| Outcome | P value |
|---|---|
| Postoperative AKIIron deficiency anemia vs Normal iron and hemoglobin · persisted after adjustment | P = 0.006 |
Original publication
Association Between Preoperative Iron Deficiency and Postoperative Outcomes in Children Undergoing Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 15 May 2026. doi:10. 1053/ j. jvca. 2026. 05. 030
Composed by AI from the published abstract and checked against it. How Briefs are made →