ICU sedation, delirium & recovery

Association between the development of intensive care unit-acquired weakness and body composition at intensive care unit admission: A descriptive study

J Crit CarePublished Retrospective cohort study

Authors' conclusion

ICU-AW patients had poorer cellular nutritional status but similar skeletal muscle mass at ICU admission compared to non-ICU-AW patients.

Study context

Population
Mixed intensive care unit (ICU) patients in Japan who walked unassisted before admission, received rehabilitation post-admission and survived ≥48 hanalysed
Participants
282 patients
Exposure
ICU-acquired weakness (ICU-AW) vs non-ICU-AW
  • ICU-AWn = 28
Outcome
Body composition by bioelectrical impedance analysis (BIA) at ICU admission
Follow-up
ICU admission
Methodological detailssingle-centre, descriptive
  • Single-centre
  • Descriptive

Main finding

As reported in the abstract

Body composition (BIA) at ICU admission
  • ICU-AW vs non-ICU-AW: P < 0.01
  • ICU-AW vs non-ICU-AW: P < 0.01
  • ICU-AW vs non-ICU-AW: P = 0.07

Observational data: associations, not effects.

Further findings

OutcomeICU-AWNon-ICU-AWP value
Age79 (IQR 72–86)70 (IQR 61–77)P < 0.01
SOFA score8 (IQR 5–13)3 (IQR 2–6)P < 0.01
ICU-AW incidence
9.9 % · 28

Original publication

Association between the development of intensive care unit-acquired weakness and body composition at intensive care unit admission: A descriptive study. J Crit Care. Published 18 October 2024. doi:10.1016/j.jcrc.2024.154933

Composed by AI from the published abstract and checked against it. How Briefs are made →

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