Perioperative medicine & outcomes
Association Between the FRAIL Scale and Postoperative Complications in Older Surgical Patients: A Systematic Review and Meta-Analysis
Authors' conclusion
As measured by the FRAIL scale, frailty was associated with 30-day mortality, 6-month mortality, postoperative complications, and postoperative delirium.
Study context
- Population
- Older surgical patients
- Participants
- 4,479 patients · 18 studies
- Comparison
- Frail vs non-frail by the FRAIL scale
- Outcome
- Mortality
Methodological detailsRisk of bias (QUIPS tool) low in 16 of 18 studies
- Risk of bias (QUIPS tool) low in 16 of 18 studies
Pooled result
As reported in the abstract
Mortality (8 studies meta-analysed)
Frail vs Non-frailOdds ratio (95% CI)P value
30-day mortality
6.62(2.80–15.61)
P < 0.016-month mortality
2.97(1.54–5.72)
P < 0.011-year mortality
1.54(0.91–2.58)
P = 0.11Further pooled results
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Postoperative complications | 3.11 (2.06–4.68) | P < 0.01 | |
| Postoperative delirium | 2.65 (1.85–3.80) | P < 0.01 | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Association Between the FRAIL Scale and Postoperative Complications in Older Surgical Patients: A Systematic Review and Meta-Analysis. Anesth Analg. Published 29 November 2022. doi:10.
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