Pain medicine

Association of cannabis use with patient-reported pain measures among adults with chronic pain in US states with medical cannabis programs

Reg Anesth Pain MedPublished Cross-sectional study

Main finding · Pain intensityResult — go to the resultScore difference 1.03 95% CI 0.05–2.02

Authors' conclusion

People with chronic non-cancer pain who used cannabis for pain reported non-clinically meaningful worse pain measures and greater burden of chronic pain conditions than their counterparts who never used cannabis.

Study context

Population
US adults with chronic non-cancer pain in 36 states and DC with active medical cannabis programs, March to April 202257% female, 69% white
Participants
1,628 adults
Exposure
Active or past vs never cannabis use for chronic pain
  • Activen = 352
  • Pastn = 137
  • Nevern = 1,139reference
Outcome
Pain intensity
Methodological detailsrepresentative sample, adjusted models
  • Representative sample
  • Adjusted models

Main finding

As reported in the abstract

Score difference

1.03

95% CI 0.05–2.02

Observational data: associations, not effects.

Further findings

OutcomeDifference (95% CI)
Number of chronic pain diagnosesActive vs Never0.45 (0.06–0.83)
OutcomeScore difference (95% CI)
Pain interferenceActive vs Never · adjusted models1.82 (0.99–2.65)
Widespread Pain IndexActive vs Never0.56 (0.26–0.86)

Original publication

Association of cannabis use with patient-reported pain measures among adults with chronic pain in US states with medical cannabis programs. Reg Anesth Pain Med. Published 3 November 2023. doi:10.1136/rapm-2023-104833

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