Association of cannabis use with patient-reported pain measures among adults with chronic pain in US states with medical cannabis programs
Main finding · Pain intensityResult — go to the resultScore difference 1.03 95% CI 0.05–2.02Authors' conclusion
People with chronic non-cancer pain who used cannabis for pain reported non-clinically meaningful worse pain measures and greater burden of chronic pain conditions than their counterparts who never used cannabis.
Study context
- Population
- US adults with chronic non-cancer pain in 36 states and DC with active medical cannabis programs, March to April 202257% female, 69% white
- Participants
- 1,628 adults
- Exposure
- Active or past vs never cannabis use for chronic pain
- Activen = 352
- Pastn = 137
- Nevern = 1,139reference
- Outcome
- Pain intensity
Methodological detailsrepresentative sample, adjusted models
- Representative sample
- Adjusted models
Main finding
As reported in the abstract
Score difference
1.03
95% CI 0.05–2.02
Observational data: associations, not effects.
Further findings
| Outcome | Difference (95% CI) | |
|---|---|---|
| Number of chronic pain diagnosesActive vs Never | 0.45 (0.06–0.83) | |
| −0.500.51Difference (linear scale) |
| Outcome | Score difference (95% CI) |
|---|---|
| Pain interferenceActive vs Never · adjusted models | 1.82 (0.99–2.65) |
| Widespread Pain IndexActive vs Never | 0.56 (0.26–0.86) |
Original publication
Association of cannabis use with patient-reported pain measures among adults with chronic pain in US states with medical cannabis programs. Reg Anesth Pain Med. Published 3 November 2023. doi:10. 1136/ rapm-2023-104833
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