Pediatric anesthesia & critical care
Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children
Authors' conclusion
Easily obtainable hemogram-derived inflammatory markers, particularly SII, may be useful for identifying children at increased risk of preoperative anxiety and EA in children.
Study context
- Population
- Children aged 5–12 years, ASA I–II, undergoing anaesthesia
- Participants
- 350 children
- Exposure
- Children with vs without emergence agitation (EA): hemogram-derived inflammatory markers
- EAn = 130
- Outcome
- Relationship of hemogram-derived inflammatory markers with preoperative anxiety and EA
Main finding
As reported in the abstract
EA incidence and inflammatory markers
EA
37.1%
130
EA vs No EA: P = 0.018 · EA vs No EA: 0.005 · EA vs No EA: 0.001 · EA vs No EA: 0.001 · EA vs No EA: P = 0.042 · EA vs No EA: P < 0.001
Observational data: associations, not effects.
Further findings
Preoperative anxiety (modified Yale Preoperative Anxiety Scale)
- Preoperative anxiety observed
- 103 (29.4%)
- Higher white blood cell counts in anxious children (p = 0.026)
- Younger age, anxious parents and elevated SII independently associated with preoperative anxiety (regression)
Original publication
Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children. Paediatr Anaesth. Published 18 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →