Perioperative medicine & outcomes

Association of rapid response system with clinical outcomes after surgery under general anesthesia

J Clin AnesthPublished Population-based cohort study

Authors' conclusion

The RRS group had lower 30-day and 90-day mortality rates than the non-RRS group after surgery under general anesthesia. Moreover, RRS was associated with a lower rate of CPR episodes resulting from cardiac arrest in patients undergoing general anesthesia after surgery.

Study context

Population
Patients who underwent surgery under GA in South Korea, January 1, 2021 to December 31, 2021447,998 propensity score (PS)-matched
Participants
1,416,844 patients
Exposure
Hospitals with rapid response system (RRS) vs without RRS
  • RRSn = 512,911
  • non-RRSn = 903,933reference
Outcome
30-day mortality, 90-day mortality, and CPR performance in the event of cardiac arrest
Methodological detailsnationwide database, propensity score matched
  • Nationwide database
  • Propensity score matched

Main finding

As reported in the abstract

30-day mortality, 90-day mortality and CPR (PS-matched cohort)
RRS vs non-RRSOdds ratio (95 % CI)P value
30-day mortality, 7 % lower
0.93(0.89–0.97)
P = 0.001
90-day mortality, 6 % lower
0.94(0.91–0.97)
P < 0.001
CPR, 9 % lower
0.91(0.83–0.98)
P = 0.020

Observational data: associations, not effects.

Original publication

Association of rapid response system with clinical outcomes after surgery under general anesthesia. J Clin Anesth. Published 15 January 2025. doi:10.1016/j.jclinane.2025.111749

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