Obstetric anesthesia

Associations between postpartum pain type, pain intensity and opioid use in patients with and without opioid use disorder: a cross-sectional study

Br J AnaesthPublished Cross-sectional study

Authors' conclusion

Postpartum pain type was associated with pain intensity and opioid use.

Study context

Population
Postpartum people with or without opioid use disorder after childbirth in a 4-month period44,522 pain scores
Participants
2,610 people
Exposure
Postpartum pain types in people with and without opioid use disorder (OUD)
Outcome
Co-primary: pain intensity (0-10 scale) and total inpatient oxycodone (mg)
Methodological detailssingle-centre, multivariable linear mixed-effects models
  • Single-centre
  • Multivariable linear mixed-effects models

Main finding

As reported in the abstract

Pain intensity and total oxycodone by pain type
Pain types associated with pain intensity
P<0.001
Affective pain associated with higher total oxycodone dose vs no affective pain (between-person)
difference 1.04 mg, P<0.001

Observational data: associations, not effects.

Further findings

Pain intensity with affective pain (OUD subgroup)

Within-person: pain scores 1 point higher when affective pain present
P = 0.002
Between-person: pain scores 6 points higher with affective pain
P = 0.048

Total oxycodone dose with nociceptive/neuropathic pain (OUD subgroup)

mg

Within-person: higher total oxycodone dose
1.6
Between-person: higher total oxycodone dose
11.4

Original publication

Associations between postpartum pain type, pain intensity and opioid use in patients with and without opioid use disorder: a cross-sectional study. Br J Anaesth. Published 10 November 2022. doi:10.1016/j.bja.2022.09.029

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