Associations between postpartum pain type, pain intensity and opioid use in patients with and without opioid use disorder: a cross-sectional study
Authors' conclusion
Postpartum pain type was associated with pain intensity and opioid use.
Study context
- Population
- Postpartum people with or without opioid use disorder after childbirth in a 4-month period44,522 pain scores
- Participants
- 2,610 people
- Exposure
- Postpartum pain types in people with and without opioid use disorder (OUD)
- Outcome
- Co-primary: pain intensity (0-10 scale) and total inpatient oxycodone (mg)
Methodological detailssingle-centre, multivariable linear mixed-effects models
- Single-centre
- Multivariable linear mixed-effects models
Main finding
As reported in the abstract
Pain intensity and total oxycodone by pain type
- Pain types associated with pain intensity
- P<0.001
- Affective pain associated with higher total oxycodone dose vs no affective pain (between-person)
- difference 1.04 mg, P<0.001
Observational data: associations, not effects.
Further findings
Pain intensity with affective pain (OUD subgroup)
- Within-person: pain scores 1 point higher when affective pain present
- P = 0.002
- Between-person: pain scores 6 points higher with affective pain
- P = 0.048
Total oxycodone dose with nociceptive/neuropathic pain (OUD subgroup)
mg
- Within-person: higher total oxycodone dose
- 1.6
- Between-person: higher total oxycodone dose
- 11.4
Original publication
Associations between postpartum pain type, pain intensity and opioid use in patients with and without opioid use disorder: a cross-sectional study. Br J Anaesth. Published 10 November 2022. doi:10. 1016/ j. bja. 2022. 09. 029
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