Associations Between Time to Reduction and Complications in Patients With First-Time Total Hip Arthroplasty Dislocation: A Retrospective Cohort Study
Authors' conclusion
Most patients underwent closed reduction within 12 hours, without increased risk of complications. Reductions exceeding 12 hours of waiting time were associated with longer post-reduction LOS, even when adjusting for known confounders. Further delays were associated with increased odds of mortality, delirium, and infections.
Study context
- Population
- Adults (≥18 years) with first-time total hip arthroplasty (THA) dislocation undergoing closed reduction in the operating theater, Capital and Zealand Regions of Denmark, 2017–2025
- Participants
- 3,494 reductions
- Exposure
- Time to closed reduction: 12-18 h, 18-24 h, >24 h vs <3 h
- Outcome
- Post-reduction LOS (linear regression adjusted for predefined confounders)
Methodological detailsobservational, multicentre (Capital and Zealand Regions of Denmark)
- Observational
- Multicentre (Capital and Zealand Regions of Denmark)
Main finding
As reported in the abstract
Post-reduction LOS
<3 hours
15.4
median · IQR 10.5–23.4 · hours
Each group vs <3 hoursIncrease, hours (95% CI)P value
12-18 hours
50.6(30.4–71.5)
P < 0.00118-24 hours
197(146–249)
P < 0.001Beyond 24 hours
137(119–154)
P < 0.001Observational data: associations, not effects.
Secondary outcomes
Reductions within 12 hours of admission
- Performed within 12 hours of admission
- 86.7%
Mortality, delirium, infection
- Post-reduction length of stay (LOS) beyond 24 hours statistically significantly associated with increased mortality, delirium, and infection
Original publication
Associations Between Time to Reduction and Complications in Patients With First-Time Total Hip Arthroplasty Dislocation: A Retrospective Cohort Study. Anesth Analg. Published 22 May 2026. doi:10.
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