Cardiac arrest & resuscitation

Automated External Defibrillator Pad Application Before Emergency Medical Service (EMS) Arrival in Pediatric Out-of-Hospital Cardiac Arrest

JAMA Netw OpenPublished Prospective cohort study

Authors' conclusion

In this cohort study from Japan, approximately 5% of pediatric patients with OHCA received AED pad application before EMS arrival, and AED pad application was associated with higher odds of 1-month survival with a favorable neurological outcome.

Study context

Population
Pediatric out-of-hospital cardiac arrest (OHCA) patients aged 0 to 17 years with resuscitation attempted before EMS arrival, Japan, 2021–2023analysed
Participants
3,352 patients
Exposure
Automated external defibrillator (AED) pad application before EMS arrival vs none; factors associated with AED pad application
Outcome
AED pad application before EMS arrival; 1-month survival with favorable neurological outcome (cerebral performance category 1 or 2)
Methodological detailsnationwide, population-based, registry (All-Japan Utstein Registry), multivariable logistic regression
  • Nationwide
  • Population-based
  • Registry (All-Japan Utstein Registry)
  • Multivariable logistic regression

Main finding

As reported in the abstract

AED pad application before EMS arrival
Adjusted odds ratio (95% CI)
Infants vs Adolescents
0.28(0.13–0.47)
Younger children vs Adolescents
0.22(0.10–0.49)
Home vs Another public area
0.06(0.03–0.11)
Nighttime vs Daytime
0.52(0.33–0.82)
School vs Another public area
6.74(3.73–12.21)
Bystander CPR
28.69(12.91–63.75)
AED pad application before EMS arrival, overall
185 (5.5%)

Observational data: associations, not effects.

Further findings

OutcomeaOR (95% CI)
1-month survival with favorable neurological outcomeAED pad application vs Non-AED pad application3.11 (1.30–7.44)

1-month survival with favorable neurological outcome

aOR (95% CI)
Ventricular fibrillation as first documented rhythm27.49 (13.95–54.19)

Original publication

Automated External Defibrillator Pad Application Before EMS Arrival in Pediatric Out-of-Hospital Cardiac Arrest. JAMA Netw Open. Published 1 July 2026. doi:10.1001/jamanetworkopen.2026.25069

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