Baseline haemoglobin variability by measurement technique in pregnant people on the day of childbirth

AnaesthesiaPublished Prospective observational study

Authors' conclusion

HemoCue capillary measurement under-estimated haemoglobin and Masimo haemoglobin measurement over-estimated, limiting their clinical use.

Study context

Population
Pregnant people on the day of planned vaginal birth
Participants
180 people
Exposure
Venous and capillary HemoCue and Masimo Rad-67 Pulse CO-Oximeter Hb vs laboratory Hb
Outcome
Agreement with laboratory haemoglobin (bias and limits of agreement)
Follow-up
Day of childbirth
Methodological detailsmethod comparison (Bland-Altman analysis)
  • Method comparison (Bland-Altman analysis)

Main finding

As reported in the abstract

Bias vs laboratory Hb
Each group vs laboratoryMean difference (bias), g.l-1 (95% CI)
HemoCue venousSD 7.54; limits of agreement −14.10-15.46 g.l-1; agreement range 29.6 g.l-1; acceptable
0.7(−0.43-1.79)
HemoCue capillarySD 14.12; limits of agreement - 14.42-40.93 g.l-1; agreement range 55.3 g.l-1; unacceptable
13.3(11.17–15.34)
MasimoSD 11.15; limits of agreement −35.85 to 7.87 g.l-1; agreement range 43.7 g.l-1; bias unacceptable
−14.0(−15.63 to −12.34)

Observational data: associations, not effects.

Further findings

Anaemia (Hb < 110 g.l-1)

People with anaemia
5 (2.8%)

Original publication

Baseline haemoglobin variability by measurement technique in pregnant people on the day of childbirth. Anaesthesia. Published 21 November 2023. doi:10.1111/anae.16174

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