Benefits of secretion clearance with high frequency percussive ventilation in tracheostomized critically ill patients: a pilot study
Authors' conclusion
Short cycles of HFPV superimposed to mechanical ventilation promoted alveolar recruitment, as suggested by improved ∆EELI, and improved oxygenation in tracheostomized patients with high load of secretion.
Study context
- Population
- Tracheostomized critically ill patients undergoing mechanical ventilation with high load of secretion
- Comparison
- Short high-frequency percussive ventilation (HFPV) cycle (10 min) superimposed on mechanical ventilation; post-treatment vs baseline
- Outcome
- Lung aeration (electrical impedance tomography (EIT)) and gas exchange
- Follow-up
- T1 (after HFPV), T2 (1 h), T3 (3 h)
Methodological detailsprospectively registered
- Prospectively registered
Main finding
As reported in the abstract
- ∆EELI significantly improved at T1, T2 and T3 vs baseline
- p < 0.05
- PaO2/FiO2 increased after treatment
- p < 0.001
- Tidal variation (TIV) unchanged
- p = 0.132
- Global inhomogeneity index (GI) unchanged
- p = 0.114
Original publication
Benefits of secretion clearance with high frequency percussive ventilation in tracheostomized critically ill patients: a pilot study. J Clin Monit Comput. Published 6 January 2023. doi:10.
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