Bilevel positive airway pressure for gastroscopy with sedation in patients at risk of hypoxemia: A prospective randomized controlled study
Authors' conclusion
BPAP therapy significantly decreased the incidence of hypoxemia in patients with OSA or overweight status who underwent gastroscopy.
Study context
- Population
- Patients aged 18–65 years with obstructive sleep apnea (OSA) or overweight status undergoing gastroscopy with sedation
- Participants
- 80 patients
- Comparison
- Bilevel positive airway pressure (BPAP) vs nasal cannula during sedated gastroscopy
- Primary endpoint
- Incidence of hypoxemia (75% < SpO2 < 90% for >5 s and <60 s)
Methodological detailssingle-centre, prospective
- Single-centre
- Prospective
Primary result
Hypoxemia
Absolute risk difference
37.5%
95% CI 21.6–53.4
P < 0.001
By group
BPAP vs Nasal cannula
absolute risk difference 37.5% (95% CI 21.6–53.4); P < 0.001
As reported in the abstract
Further findings
| Outcome | BPAP | Nasal cannula | ARD (95% CI) | P value | |
|---|---|---|---|---|---|
| Subclinical respiratory depression | 22.5% | 52.5% | 30.0% (9.8–50.2) | P = 0.006 | |
| Severe hypoxemia | 0% | 17.5% | 17.5% (5.7–29.3) | P = 0.006 | |
| −50050100Difference (linear scale) |
Total propofol dose, operation time, anesthesiologist satisfaction
- BPAP decreased total propofol dosage and operation time and improved anesthesiologist's satisfaction
Original publication
Bilevel positive airway pressure for gastroscopy with sedation in patients at risk of hypoxemia: A prospective randomized controlled study. J Clin Anesth. Published 20 December 2022. doi:10.
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