Pediatric anesthesia & critical care

Bleeding and ketorolac use in pediatric circumcision

Paediatr AnaesthPublished Retrospective cohort study

Main finding · Postoperative bleeding requiring interventionResult — go to the resultDifference 0.6% 95% CI −0.8% to 2.0%

Authors' conclusion

There was no statistically significant difference in postoperative bleeding requiring intervention between the non-ketorolac and ketorolac groups.

Study context

Population
Pediatric patients 1–18 years undergoing isolated circumcision by one urologist, 2016 to 2020
Participants
743 patients
Exposure
Intraoperative ketorolac vs no ketorolac
  • Ketorolacn = 429
  • Non-ketorolacn = 314reference
Outcome
Clinically significant bleeding (bleeding requiring intervention: absorbable hemostats, sutures, or return to the OR)
Follow-up
First 24 h
Methodological detailssingle-centre, single urologist
  • Single-centre
  • Single urologist

Main finding

Postoperative bleeding requiring intervention

Difference

0.6%

95% CI −0.8% to 2.0%

P = 0.403

Events by group

Ketorolac vs Non-ketorolac
difference 0.6% (95% CI −0.8% to 2.0%); P = 0.403

As reported in the abstract

Observational data: associations, not effects.

Original publication

Bleeding and ketorolac use in pediatric circumcision. Paediatr Anaesth. Published 29 March 2023. doi:10.1111/pan.14661

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