Neuroanesthesia & neurocritical care
Brain death determination in patients with veno-arterial extracorporeal membrane oxygenation: A systematic study to address the Harlequin syndrome
Authors' conclusion
Simultaneous paCO2-analysis from right and left distal arterial lines is the method of choice to reduce the risk of adverse effects (e.g. severe respiratory acidosis) while performing AT in VA-ECMO patients during BD determination.
Study context
- Population
- Venoarterial extracorporal membrane oxygenation (VA-ECMO) patients undergoing brain death determination with apnea testing
- Participants
- 27 patients
- Comparison
- Variant 2 vs Variant 1
- Outcome
- Difference in paCO2-levels between paired sampling sites
- Follow-up
- Start of apnea testing
Main finding
As reported in the abstract
paCO2-difference · start of AT
P = 0.001
Further findings
paCO2-difference · end of AT · variant 2 increased; variant 1 unchanged
P = 0.002
Original publication
Brain death determination in patients with veno-arterial extracorporeal membrane oxygenation: A systematic study to address the Harlequin syndrome. J Crit Care. Published 22 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →