Perioperative medicine & outcomes

Brain Structural and Functional Changes Associated With Postoperative Neurocognitive Disorders: Research Update

Anesth AnalgPublished Narrative review

Study context

Population
Elderly patients with postoperative neurocognitive disorders (PNDs)

Main finding

As reported in the abstract

  • Risk factors incl. surgical trauma and stress mediate systemic inflammation towards neuroinflammation, causing brain structural and functional changes (PND)
  • Preliminary evidence on EEG, functional near-infrared spectroscopy, functional magnetic resonance and positron emission tomography imaging for postoperative CNS monitoring

Original publication

Brain Structural and Functional Changes Associated With Postoperative Neurocognitive Disorders: Research Update. Anesth Analg. Published 19 February 2025. doi:10.1213/ane.0000000000007404

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