Pediatric anesthesia & critical care
Clinical Outcomes, Blood Utilization, and Ethical Considerations for Pediatric Patients in a Bloodless Medicine and Surgery Program
Main finding · Composite morbidityResult — go to the resultOdds ratio 0.37 95% CI 0.12–1.11Authors' conclusion
Pediatric patients receiving bloodless care exhibited similar clinical outcomes compared to patients receiving standard care, although larger studies with adequate power are needed to confirm this finding.
Study context
- Population
- Pediatric inpatients (<18 years of age), single institution, June 2012 to June 2016
- Participants
- 196 vs 37,271
- Exposure
- Bloodless care vs standard care
- Bloodless caren = 196
- Standard caren = 37,271reference
- Outcome
- Composite:
- Morbidity
- Mortality
Methodological detailssingle-institution, multivariable analysis
- Single-institution
- Multivariable analysis
Main finding
Composite morbidity
Odds ratio
0.37
95% CI 0.12–1.11
P = 0.077
By group
Bloodless care vs Standard care
OR 0.37 (95% CI 0.12–1.11); P = 0.077
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
Patients receiving allogeneic blood component
P = 0.14
Patients receiving allogeneic blood component
- Most common indications: perioperative bleeding and anemia of prematurity; none administered under a court order
Individual morbid events, LOS, total hospital charges/costs
- Not significantly different between the 2 groups
Original publication
Clinical Outcomes, Blood Utilization, and Ethical Considerations for Pediatric Patients in a Bloodless Medicine and Surgery Program. Anesth Analg. Published 12 January 2024. doi:10. 1213/ ane. 0000000000006776
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