Pediatric anesthesia & critical care

Clinical Outcomes, Blood Utilization, and Ethical Considerations for Pediatric Patients in a Bloodless Medicine and Surgery Program

Anesth AnalgPublished Retrospective cohort study

Main finding · Composite morbidityResult — go to the resultOdds ratio 0.37 95% CI 0.12–1.11

Authors' conclusion

Pediatric patients receiving bloodless care exhibited similar clinical outcomes compared to patients receiving standard care, although larger studies with adequate power are needed to confirm this finding.

Study context

Population
Pediatric inpatients (<18 years of age), single institution, June 2012 to June 2016
Participants
196 vs 37,271
Exposure
Bloodless care vs standard care
  • Bloodless caren = 196
  • Standard caren = 37,271reference
Outcome
Composite:
  • Morbidity
  • Mortality
Methodological detailssingle-institution, multivariable analysis
  • Single-institution
  • Multivariable analysis

Main finding

Composite morbidity

Odds ratio

0.37

95% CI 0.12–1.11

P = 0.077

By group

Bloodless care vs Standard care
OR 0.37 (95% CI 0.12–1.11); P = 0.077

As reported in the abstract

Observational data: associations, not effects.

Secondary outcomes

Patients receiving allogeneic blood component

P = 0.14

Patients receiving allogeneic blood component

Most common indications: perioperative bleeding and anemia of prematurity; none administered under a court order

Individual morbid events, LOS, total hospital charges/costs

Not significantly different between the 2 groups

Original publication

Clinical Outcomes, Blood Utilization, and Ethical Considerations for Pediatric Patients in a Bloodless Medicine and Surgery Program. Anesth Analg. Published 12 January 2024. doi:10.1213/ane.0000000000006776

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