ICU sedation, delirium & recovery
Cognitive Rehabilitation Interventions in the Intensive Care Unit: A Systematic Integrative Review
Authors' conclusion
Multi-component cognitive rehabilitation appeared clinically applicable, but effects on patient-important outcomes were uncertain.
Study context
- Population
- Adult ICU patients receiving, or healthcare professionals delivering, early cognitive rehabilitation initiated in the ICU27 studies
- Outcome
- Cognitive rehabilitation interventions delivered during the ICU stay and the healthcare professionals providing them
Methodological detailsPRISMA, RoB2 and ROBINS-I risk of bias assessment
- PRISMA
- RoB2 and ROBINS-I risk of bias assessment
Main finding
As reported in the abstract
Interventions and providers
- Four intervention categories: orientation and multisensory stimulation; Activities of daily living (ADL)-focused functional occupational therapy; early mobilization and physical rehabilitation; technology-based sensory and affective stimulation (music or virtual reality)
- 4
Further findings
Cognitive measures
- Multi-component programs combining cognitive and physical elements indicated possible benefits for selected cognitive measures
Delirium and ADL
- Effect estimates inconsistent; in several studies based on secondary or exploratory analyses
Ventilator-free days, health-related quality of life, survival
- Inconsistent, with substantial heterogeneity in outcome definitions, measurement tools and assessment time points
Original publication
Cognitive Rehabilitation Interventions in the Intensive Care Unit: A Systematic Integrative Review. Acta Anaesthesiol Scand. Published 24 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →