Obstetric anesthesia

Combined spinal‐epidural vs. dural puncture epidural techniques for labour analgesia: a randomised controlled trial*

AnaesthesiaPublished Randomised controlled trial

Primary resultResult — go to the resultRelative risk 0.75 95% CI 0.40–1.39

Authors' conclusion

There were no significant differences in the quality of labour analgesia following initiation of a combined spinal-epidural compared with a dural puncture epidural technique.

Study context

Population
Term parturients requesting labour epidural analgesiaincluded in the analysis
Participants
One hundred participants
Comparison
CSE vs dural puncture epidural for labour analgesia initiation
  • CSEn = 48
  • Dural puncture epiduraln = 52reference
Primary endpoint
Quality of labour analgesia: composite of asymmetric block after 30 min (sensory level difference >2 dermatomes), epidural top-ups, catheter adjustment, catheter replacement, failed conversion to neuraxial anaesthesia for caesarean delivery
Methodological detailsMaintenance with PCEA plus programmed intermittent epidural boluses
  • Maintenance with PCEA plus programmed intermittent epidural boluses

Primary result

As reported in the abstract

Relative risk

0.75

95% CI 0.40–1.39

P = 0.486

By group

Dural puncture epidural vs CSE
RR 0.75 (95% CI 0.40–1.39); P = 0.486

Further findings

Median

OutcomeCSEDural puncture epiduralP value
Pain scores · 15 minSignificantly lower with CSE0 (IQR [range] 0-1[0-8])1 (IQR [range] 0-4 [0-10])P = 0.018

Original publication

Combined spinal‐epidural vs. dural puncture epidural techniques for labour analgesia: a randomised controlled trial*. Anaesthesia. Published 7 November 2024. doi:10.1111/anae.16433

Composed by AI from the published abstract and checked against it. How Briefs are made →

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