Comparing the analgesic effect of regional nerve block technique in laparoscopic nephrectomy: A systematic review and network meta-analysis
Authors' conclusion
Analysis of existing evidence suggests that PreOp QLB demonstrates a superior advantage over other interventions, significantly reducing 24-h postoperative OME, 6-h postoperative OME, rescue analgesia usage, and the incidence of postoperative nausea and vomiting, as well as extending time to first opioid use.
Study context
- Population
- Patients undergoing laparoscopic nephrectomy
- Comparison
- Regional nerve block techniques for post-laparoscopic nephrectomy pain
- Outcome
- Cumulative oral morphine equivalent (OME) consumption
- Follow-up
- 24 h postoperatively
Methodological detailsBayesian framework
- Bayesian framework
Pooled result
As reported in the abstract
24-h postoperative OME consumption · 24 h
MD (95 % CI)
PreOp QLBlow-quality evidence
−31.23(−54.99 to −9.95)
PreOp ESBmoderate-quality evidence
−44.44(−88.03 to −0.97)
Further pooled results
Direct comparisons: Oral morphine equivalent (OME) at 24 h, 6 h and intraop, time to first opioid, patient satisfaction, PONV
- Interventions reduced OME at 24 h, 6 h and intraop, extended time to first opioid use, improved patient satisfaction and reduced PONV
Original publication
Comparing the analgesic effect of regional nerve block technique in laparoscopic nephrectomy: A systematic review and network meta-analysis. J Clin Anesth. Published 7 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →