Comparison of labor analgesia efficacy between single-orifice and multiorifice wire-reinforced catheters during programmed intermittent epidural boluses: a randomized controlled clinical trial
Authors' conclusion
Single-orifice catheters used for programmed intermittent epidural bolus at 480 mL/hour for epidural labor analgesia had improved analgesic efficacy than multiorifice catheters.
Study context
- Population
- Healthy nulliparous women with singleton pregnancy, 2–5 cm cervical dilation, requesting neuraxial labor analgesia
- Participants
- 182 women
- Comparison
- Single-orifice vs Multiorifice
- Primary endpoint
- Proportion of parturients with adequate analgesia
- Follow-up
- 20 min after the initial bolus
Methodological detailsAugust to November 2021, Epidural analgesia with 0.1% ropivacaine and 0.3 µg/mL sufentanil; 10 mL bolus every 45 min at 480 mL/hour
- August to November 2021
- Epidural analgesia with 0.1% ropivacaine and 0.3 µg/mL sufentanil; 10 mL bolus every 45 min at 480 mL/hour
Primary result
As reported in the abstract
Adequate analgesia · 20 min
95% CI 1.3%–29%; P = 0.03
Further findings
S2 sensory blockade · 20 min
(95% CI −30% to 1%) · P = 0.03
Time to adequate analgesia
(95% CI 0.1–0.7) · P < 0.01
Ropivacaine consumption per hour
(95% CI 0.2–0.8) · P < 0.001
Original publication
Comparison of labor analgesia efficacy between single-orifice and multiorifice wire-reinforced catheters during programmed intermittent epidural boluses: a randomized controlled clinical trial. Reg Anesth Pain Med. Published 9 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →