Comparison of ventilation modes in non-traumatic out-of-hospital cardiac arrest: SYMEVECA phase 2
Authors' conclusion
Successful resuscitation may vary according to ventilation mode
Study context
- Population
- Adults with non-traumatic OHCA attended by an EMS, April-2021 to September-2024252 excluded
- Participants
- 773 adults
- Exposure
- CCSV vs IPPV vs manual resuscitator bag ventilation during CPR
- CCSVn = 100
- IPPVn = 145
- Bagn = 276reference
- Outcome
- Survival with good neurological recovery (CPC 1-2)
- Follow-up
- Hospital discharge or 28 days
Methodological detailspragmatic
- Pragmatic
Main finding
As reported in the abstract
Survival with good neurological outcome
P = 0.07
Observational data: associations, not effects.
Further findings
Venous pCO2 · 15 min after tracheal intubation or ROSC
ROSC
| Outcome | CCSV | IPPV | Bag |
|---|---|---|---|
| Venous pH (patients with venous control sample) · 15 min after tracheal intubation or ROSC | 7.01 ± 0.15 | 7.00 ± 0.14 | 6.96 ± 0.15 |
- Venous pH (patients with venous control sample): p = 0.02
- Venous pCO2: p = 0.13
- ROSC: p = 0.08
Original publication
Comparison of ventilation modes in non-traumatic out-of-hospital cardiac arrest: SYMEVECA phase 2. Resuscitation. Published 21 May 2025. doi:10.
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