Perioperative medicine & outcomes

Contextual nonmedical health factors and critical care-related outcomes: a systematic review

Crit CarePublished Systematic review

Authors' conclusion

Among five SDoH domains, economic stability was found to be the top investigated SDoH category for critical care-related outcomes. Contextual SDoH variables, indicating more vulnerable and adverse conditions, were associated with higher ICU admissions, greater need for ICU resource utilization, longer ICU duration, higher likelihood of developing critical illnesses, worsened life quality following ICU discharge, and higher mortality.

Study context

Population
United States (US) clinical studies with intensive care unit (ICU) patients using contextual (area-based) social determinants of health (SDoH) from publicly available data sources
Participants
87 publications
Comparison
Association between contextual SDoH from publicly available databases and critical care-related outcomes
Outcome
Association of contextual SDoH with critical care-related outcomes (included publications)
Methodological detailsSearch of Web of Science, PubMed, Cochrane and Embase (search date June 8th, 2025)
  • Search of Web of Science, PubMed, Cochrane and Embase (search date June 8th, 2025)

Pooled result

As reported in the abstract

Publications identified

87

Publications with pediatric patients

44

Publications with adult patients

40

Publications with a mixture of pediatric and adult patients

3

Original publication

Contextual nonmedical health factors and critical care-related outcomes: a systematic review. Crit Care. Published 7 December 2025. doi:10.1186/s13054-025-05622-1

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