Perioperative medicine & outcomes

Continuous peri-operative glucose monitoring in noncardiac surgery: A systematic review

Eur J AnaesthesiolPublished Systematic review

Authors' conclusion

Due to the limited number of controlled studies, the impact of CGM on postoperative glycaemic control and complications compared with point-of-care testing remains unknown.

Study context

Population
Patients with a continuous glucose monitoring (CGM) device during the peri-operative period in noncardiac surgery (closed-loop insulin systems excluded)
Participants
1,016 patients · 26 studies
Comparison
Diabetes mellitus, bariatric surgery vs Diabetes mellitus, major surgery vs Nondiabetes mellitus
Outcome
Glycaemic profile (normal range 3.9 to 10.0 mmol l −1)

Pooled result

As reported in the abstract

Glycaemic profile (mean glucose; % time below, in and above range)
GroupValueTime below rangeTime in rangeTime above range
Diabetes mellitus, bariatric surgerymean 5.6 (SD 0.5) mmol l −115.4 ± 8.6%75.3 ± 5.5%9.6 ± 6.7%
Diabetes mellitus, major surgerymean 9.6 (SD 1.1) mmol l −19.5 ± 9.1%56.3 ± 13.5%30.6 ± 13.9%
Nondiabetes mellitusmean 6.4 (SD 0.6) mmol l −16.7 ± 8.4%84.6 ± 15.5%11.2 ± 4.9%

Value

Diabetes mellitus, bariatric surgerymean 5.6 (SD 0.5) mmol l −1
Diabetes mellitus, major surgerymean 9.6 (SD 1.1) mmol l −1
Nondiabetes mellitusmean 6.4 (SD 0.6) mmol l −1

Time below range

Diabetes mellitus, bariatric surgery15.4 ± 8.6%
Diabetes mellitus, major surgery9.5 ± 9.1%
Nondiabetes mellitus6.7 ± 8.4%

Time in range

Diabetes mellitus, bariatric surgery75.3 ± 5.5%
Diabetes mellitus, major surgery56.3 ± 13.5%
Nondiabetes mellitus84.6 ± 15.5%

Time above range

Diabetes mellitus, bariatric surgery9.6 ± 6.7%
Diabetes mellitus, major surgery30.6 ± 13.9%
Nondiabetes mellitus11.2 ± 4.9%

Further pooled results

Peri-operative complications

Reported in only one comparative study; similar in CGM and control groups

Safety

Device dysfunction (accidental removal, sensor or reader issues)

Cases with device dysfunction
9.21%

Device-related adverse events

Rare and underreported

Original publication

Continuous peri-operative glucose monitoring in noncardiac surgery: A systematic review. Eur J Anaesthesiol. Published 7 November 2024. doi:10.1097/eja.0000000000002095

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