Pain medicine

Correlation between epidural space depth measured with ultrasound and MRI compared to clinical loss of resistance when performing lumbar epidural steroid injection

Reg Anesth Pain MedPublished Prospective diagnostic accuracy study

Authors' conclusion

MRI measurements are preferable over US for preprocedural assessment of patients receiving lumbar ESIs for predicting CLORD.

Study context

Population
Patients receiving fluoroscopy-guided lumbar epidural steroid injections at an academic chronic pain clinic
Participants
60 patients
Comparison
MRI and ultrasound (US) epidural space depth vs clinical loss of resistance depth
Outcome
Equivalence of imaging-measured epidural space depth with CLORD (0.5 equivalency margin)
Methodological detailsequivalence testing (two one-sided tests, 0.5 margin)
  • Equivalence testing (two one-sided tests, 0.5 margin)

Performance

As reported in the abstract

Difference in epidural space depth vs CLORD
Each group vs CLORDMean difference, cm
MRIequivalent
−0.2(95% CI −0.39 to −0.11)
US transversenot equivalent; underestimated CLORD
−0.98(90% CI −1.8 to −0.77)
US parasagittal oblique · not equivalent; underestimated clinical loss of resistance depth (CLORD)
mean difference −0.79 cm (90% CI −1.0 to −5.9)

Further findings

Intraclass correlation coefficient

OutcomeMRIUS transverseUS parasagittal oblique
Intraclass correlation coefficient with CLORDMixed effects models0.850.650.73

Original publication

Correlation between epidural space depth measured with ultrasound and MRI compared to clinical loss of resistance when performing lumbar epidural steroid injection. Reg Anesth Pain Med. Published 23 January 2024. doi:10.1136/rapm-2023-105135

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