ICU sedation, delirium & recovery
Critically ill metastatic cancer patients returning home after unplanned ICU stay: an observational, multicentre retrospective study
Authors' conclusion
More than one out of three metastatic cancer patients could return home within 3 months after an unplanned admission to the ICU. Previous performance and nutritional status, ongoing specific treatment and low severity of the acute illness were found to be predictive for return home.
Study context
- Population
- Consecutive metastatic cancer patients (mainly lung cancer) with unplanned ICU admission, 2017–2020
- Participants
- 253 patients
- Outcome
- Return home
- Follow-up
- Day 90
Methodological detailsmulticentre, observational
- Multicentre
- Observational
Main finding
As reported in the abstract
Return home on day 90
Metastatic cancer patients
37.2%
94 events
Odds ratio (95% CI)P value
Performance status 0 or 1
2.18(1.21–3.93)
P = 0.010No malnutrition
2.90(1.61–5.24)
P < 0.001Female gender
2.39(1.33–4.29)
P = 0.004Recent chemotherapy
2.62(1.40–4.90)
P = 0.003SOFA score ≤ 5 on admission
2.62(1.41–4.90)
P = 0.002Observational data: associations, not effects.
Further findings
1-year mortality (independent associations)
| HR (95% CI) | P value | ||
|---|---|---|---|
| Malnutrition | 1.66 (1.18–2.22) | P = 0.003 | |
| ARF as reason for admission | 1.40 (1.10–1.95) | P = 0.043 | |
| SAPS II on admission | 1.03 (1.02–1.05) | P < 0.001 | |
| DFLSTDecisions to forgo life-sustaining therapies | 2.80 (2.04–3.84) | P < 0.001 | |
| 0.20.5125Hazard ratio (log scale) |
1-year survival
- One-year survival rate
- 28.5%
Original publication
Critically ill metastatic cancer patients returning home after unplanned ICU stay: an observational, multicentre retrospective study. Ann Intensive Care. Published 21 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →