Pediatric anesthesia & critical care

Cuffed versus uncuffed endotracheal tubes in neonates undergoing noncardiac surgeries: A randomized controlled trial

Paediatr AnaesthPublished Randomised controlled trial

Primary resultResult — go to the resultRelative risk 0.54 95% CI 0.43–0.69

Authors' conclusion

In full term neonates undergoing noncardiac surgeries, the use of cuffed ETT was associated with less need to tracheal tube exchange and less incidence of postoperative croup, without increasing the postoperative respiratory complications compared to uncuffed ETT.

Study context

Population
Neonates scheduled for noncardiac surgeries
Participants
60 vs 60
Comparison
Cuffed vs uncuffed ETT during GA
  • Cuffed ETTn = 60
  • Uncuffed ETTn = 60reference
Primary endpoint
Incidence of ETT exchange to find the appropriate ETT

Primary result

As reported in the abstract

Relative risk

0.54

95% CI 0.43–0.69

P = 0.0001

Events by treatment group

Cuffed ETT vs Uncuffed ETT
RR 0.54 (95% CI 0.43–0.69); P = 0.0001

Safety

OutcomeCuffed ETTUncuffed ETTRR (95% CI)P value
Post-extubation croup5%16.7%1.14 (1–1.29)P = 0.04

Other postoperative adverse events

Comparable between groups

Original publication

Cuffed versus uncuffed endotracheal tubes in neonates undergoing noncardiac surgeries: A randomized controlled trial. Paediatr Anaesth. Published 22 June 2024. doi:10.1111/pan.14953

Composed by AI from the published abstract and checked against it. How Briefs are made →

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