Pediatric anesthesia & critical care
Cuffed versus uncuffed endotracheal tubes in neonates undergoing noncardiac surgeries: A randomized controlled trial
Primary resultResult — go to the resultRelative risk 0.54 95% CI 0.43–0.69Authors' conclusion
In full term neonates undergoing noncardiac surgeries, the use of cuffed ETT was associated with less need to tracheal tube exchange and less incidence of postoperative croup, without increasing the postoperative respiratory complications compared to uncuffed ETT.
Study context
- Population
- Neonates scheduled for noncardiac surgeries
- Participants
- 60 vs 60
- Comparison
- Cuffed vs uncuffed ETT during GA
- Cuffed ETTn = 60
- Uncuffed ETTn = 60reference
- Primary endpoint
- Incidence of ETT exchange to find the appropriate ETT
Primary result
As reported in the abstract
Relative risk
0.54
95% CI 0.43–0.69
P = 0.0001
Events by treatment group
Cuffed ETT vs Uncuffed ETT
RR 0.54 (95% CI 0.43–0.69); P = 0.0001
Safety
| Outcome | Cuffed ETT | Uncuffed ETT | RR (95% CI) | P value | |
|---|---|---|---|---|---|
| Post-extubation croup | 5% | 16.7% | 1.14 (1–1.29) | P = 0.04 | |
| 0.512Relative risk (log scale) |
Other postoperative adverse events
- Comparable between groups
Original publication
Cuffed versus uncuffed endotracheal tubes in neonates undergoing noncardiac surgeries: A randomized controlled trial. Paediatr Anaesth. Published 22 June 2024. doi:10. 1111/ pan. 14953
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