Paediatric anaesthesia & critical care
Delayed gastric emptying in adolescent patients on GLP-1 receptor agonists with standard preoperative fasting guidelines: a prospective cohort study
Authors' conclusion
We observed that 80% of adolescents on GLP1-RAs had solids on gastric ultrasound despite having fasted for over 12 h.
Study context
- Population
- Adolescents (10–18 yr) fasted 8 h for solids and 1 h for clear liquids, single institution, June 2023–November 2024analysed
- Participants
- 67 adolescents
- Exposure
- GLP1-RA vs At-risk vs Control
- GLP1-RAn = 20
- At-riskn = 27
- Controln = 20reference
- Outcome
- Residual gastric contents on gastric ultrasound (presence of solids or gastric fluid volume ≥1.5 ml kg-1)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Solids present on gastric ultrasound
GLP1-RA vs At-risk vs Control: P < 0.001 · GLP1-RA vs At-risk vs Control: P < 0.02
Observational data: associations, not effects.
Further findings
Actual fasting duration (all patients)
- Solids, median 13 h (IQR 12-14)
- 13
- Clears, median 12 h (IQR 3.5-13)
- 12
Original publication
Delayed gastric emptying in adolescent patients on GLP-1 receptor agonists with standard preoperative fasting guidelines: a prospective cohort study. Br J Anaesth. Published 8 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →