Perioperative medicine & outcomes

Development, external validation and integration into clinical workflow of machine learning models to support pre‐operative assessment in the UK

AnaesthesiaPublished Prediction model development and external validation study

Authors' conclusion

We conclude that conducting modelling together with systems development can yield accurate prediction models that may be implemented directly into electronic health records.

Study context

Population
UK surgical patients undergoing pre-operative assessment, two NHS Trusts using different electronic record systems110,732 development
Comparison
ASA physical status prediction model vs Mortality prediction model
Outcome
Categorisation into lower- and higher-risk cohorts by predicted ASA physical status (1 or 2 vs. 3-5) and 30-day postoperative mortality risk
Methodological detailsmachine learning, two NHS Trusts, Certified electronic linkages between Smart PreOp and NHS England GP Connect to retrieve GP record data into pre-operative questionnaires
  • Machine learning
  • Two NHS Trusts
  • Certified electronic linkages between Smart PreOp and NHS England GP Connect to retrieve GP record data into pre-operative questionnaires

Performance

As reported in the abstract

Identification of lower-risk (ASA physical status 1 or 2) patients, external validation
Test or modelRecallPrecision
ASA physical status prediction model0.690.95

ASA physical status prediction model

Recall0.69
Precision0.95

Further findings

30-day postoperative mortality prediction, external validation

Mortality model discriminated well but was poorly calibrated

Original publication

Development, external validation and integration into clinical workflow of machine learning models to support pre‐operative assessment in the UK. Anaesthesia. Published 14 September 2025. doi:10.1111/anae.16777

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